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Volume 31
Issue 10
10.3390/molecules31101572
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This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Review

Micelle-Assisted Lewis and Brønsted Acid Catalysis: A Review Towards Greener and Efficient Synthesis of Polycyclic and Heteroaromatic Compounds

by
Harvinder S. Sohal
1,*,
Sanyojak Kanwal
1,
Chirag G. Makvana
2,
Navneet Kaur
1,
Haesook Han
3,
Manvinder Kaur
4,
Pradip K. Bhowmik
3,*,
Ankush Mehta
5 and
Kulwinder Singh
6
1
Materials and Natural Product Laboratory, Department of Chemistry, Chandigarh University, Gharuan, Mohali 140413, Punjab, India
2
Department of Chemistry, Faculty of Science, Gokul Global University, Sidhpur 384151, Gujarat, India
3
Department of Chemistry and Biochemistry, University of Nevada Las Vegas, 4505 S. Maryland Parkway, Box 454003, Las Vegas, NV 89154, USA
4
Chitkara School of Planning and Architecture, Chitkara University, Rajpura 140401, Punjab, India
5
School of Engineering and Technology, K. R. Mangalam University, Gurugram 122103, Haryana, India
6
Department of Physics, Graphic Era Deemed to be University, Dehradun 248002, Uttarakhand, India
*
Authors to whom correspondence should be addressed.
Molecules 2026, 31(10), 1572; https://doi.org/10.3390/molecules31101572
Submission received: 1 April 2026 / Revised: 28 April 2026 / Accepted: 5 May 2026 / Published: 8 May 2026
(This article belongs to the Section Green Chemistry)
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Abstract

Considering the expanded interest in reducing organic solvents in synthesis, surfactants and surfactant-based catalysis have been used to carry out various organic transformations in water. In recent years, the integration of Lewis and Brønsted acid catalysis with micellar systems has gained considerable attention as a powerful approach to enhance reaction efficiency while minimizing the environmental impact of synthetic processes. In this article, we depict the most recent advances in the water-interceded synthesis of different organic systems by utilizing different surfactant-type catalysts, which are important structural motifs in pharmaceuticals, agrochemicals and functional materials. Further, these methods incorporate green reaction media, mild reaction conditions, and a great yield of product with high purity in a shorter interval of time. Understanding the scope and impact of this area, authors have made efforts to collect and compile the data that indicates many named reactions, such as Friedlander annulation, aldol condensation, the Biginelli reaction, the Mannich reaction, Suzuki–Miyaura cross-coupling, etc., now take place using surfactant-based catalysts.
Keywords: surfactant catalysis; phase transfer catalysis; organic synthesis; polycyclic aromatic compounds; green synthesis surfactant catalysis; phase transfer catalysis; organic synthesis; polycyclic aromatic compounds; green synthesis
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MDPI and ACS Style

Sohal, H.S.; Kanwal, S.; Makvana, C.G.; Kaur, N.; Han, H.; Kaur, M.; Bhowmik, P.K.; Mehta, A.; Singh, K. Micelle-Assisted Lewis and Brønsted Acid Catalysis: A Review Towards Greener and Efficient Synthesis of Polycyclic and Heteroaromatic Compounds. Molecules 2026, 31, 1572. https://doi.org/10.3390/molecules31101572

AMA Style

Sohal HS, Kanwal S, Makvana CG, Kaur N, Han H, Kaur M, Bhowmik PK, Mehta A, Singh K. Micelle-Assisted Lewis and Brønsted Acid Catalysis: A Review Towards Greener and Efficient Synthesis of Polycyclic and Heteroaromatic Compounds. Molecules. 2026; 31(10):1572. https://doi.org/10.3390/molecules31101572

Chicago/Turabian Style

Sohal, Harvinder S., Sanyojak Kanwal, Chirag G. Makvana, Navneet Kaur, Haesook Han, Manvinder Kaur, Pradip K. Bhowmik, Ankush Mehta, and Kulwinder Singh. 2026. "Micelle-Assisted Lewis and Brønsted Acid Catalysis: A Review Towards Greener and Efficient Synthesis of Polycyclic and Heteroaromatic Compounds" Molecules 31, no. 10: 1572. https://doi.org/10.3390/molecules31101572

APA Style

Sohal, H. S., Kanwal, S., Makvana, C. G., Kaur, N., Han, H., Kaur, M., Bhowmik, P. K., Mehta, A., & Singh, K. (2026). Micelle-Assisted Lewis and Brønsted Acid Catalysis: A Review Towards Greener and Efficient Synthesis of Polycyclic and Heteroaromatic Compounds. Molecules, 31(10), 1572. https://doi.org/10.3390/molecules31101572

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