Solubility and Solvation Properties of Pharmaceutically Active Ionic Liquid Benzocainium Ibuprofenate in Natural Deep Eutectic Solvent Menthol–Lauric Acid
Abstract
:1. Introduction
2. Results and Discussion
2.1. Characterization of Prepared Solvent
2.2. Solubility Determination
2.3. Volumetric and Viscosity Studies
3. Materials and Methods
3.1. Solvent Preparation
3.2. Spectroscopy Analysis
3.3. Solubility Determination
3.4. Density and Viscosity Measurements
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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T (K) | 293.15 | 298.15 | 303.15 | 308.15 | 313.15 |
Vϕo (cm3·mol−1) | 345.24 | 346.50 | 347.49 | 348.17 | 349.14 |
SV (cm3·dm3/2·mol−3/2) | 8.20 | 8.87 | 9.46 | 10.19 | 11.37 |
Eφo (cm3·mol−1·K−1) | 0.2390 | 0.2142 | 0.1893 | 0.1645 | 0.1396 |
A (dm3/2·mol−1/2) | −0.0913 | −0.0703 | −0.0690 | −0.0865 | −0.0951 |
B (dm3∙mol−1) | 0.9727 | 0.8494 | 0.7960 | 0.7820 | 0.7619 |
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Panić, J.; Rapaić, M.; Gadžurić, S.; Vraneš, M. Solubility and Solvation Properties of Pharmaceutically Active Ionic Liquid Benzocainium Ibuprofenate in Natural Deep Eutectic Solvent Menthol–Lauric Acid. Molecules 2023, 28, 5723. https://doi.org/10.3390/molecules28155723
Panić J, Rapaić M, Gadžurić S, Vraneš M. Solubility and Solvation Properties of Pharmaceutically Active Ionic Liquid Benzocainium Ibuprofenate in Natural Deep Eutectic Solvent Menthol–Lauric Acid. Molecules. 2023; 28(15):5723. https://doi.org/10.3390/molecules28155723
Chicago/Turabian StylePanić, Jovana, Maksim Rapaić, Slobodan Gadžurić, and Milan Vraneš. 2023. "Solubility and Solvation Properties of Pharmaceutically Active Ionic Liquid Benzocainium Ibuprofenate in Natural Deep Eutectic Solvent Menthol–Lauric Acid" Molecules 28, no. 15: 5723. https://doi.org/10.3390/molecules28155723