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Review

Pharmacological Activities of Soursop (Annona muricata Lin.)

1
Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Bandung 45363, Indonesia
2
Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Padjadjaran, Bandung 45363, Indonesia
3
Department of Pharmacology and Clinical Pharmacy, Universitas Padjadjaran, Bandung 45363, Indonesia
*
Authors to whom correspondence should be addressed.
Academic Editors: Raffaele Capasso and Domenico Trombetta
Molecules 2022, 27(4), 1201; https://doi.org/10.3390/molecules27041201
Received: 16 November 2021 / Revised: 15 January 2022 / Accepted: 25 January 2022 / Published: 10 February 2022
Soursop (Annona muricata Lin.) is a plant belonging to the Annonaceae family that has been widely used globally as a traditional medicine for many diseases. In this review, we discuss the traditional use, chemical content, and pharmacological activities of A.muricata. From 49 research articles that were obtained from 1981 to 2021, A.muricata’s activities were shown to include anticancer (25%), antiulcer (17%), antidiabetic (14%), antiprotozoal (10%), antidiarrhea (8%), antibacterial (8%), antiviral (8%), antihypertensive (6%), and wound healing (4%). Several biological activities and the general mechanisms underlying the effects of A.muricata have been tested both in vitro and in vivo. A.muricata contains chemicals such as acetogenins (annomuricins and annonacin), alkaloids (coreximine and reticuline), flavonoids (quercetin), and vitamins, which are predicted to be responsible for the biological activity of A.muricata. View Full-Text
Keywords: soursop; Annona muricata L.; traditional medicine; pharmacological activities soursop; Annona muricata L.; traditional medicine; pharmacological activities
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MDPI and ACS Style

Mutakin, M.; Fauziati, R.; Fadhilah, F.N.; Zuhrotun, A.; Amalia, R.; Hadisaputri, Y.E. Pharmacological Activities of Soursop (Annona muricata Lin.). Molecules 2022, 27, 1201. https://doi.org/10.3390/molecules27041201

AMA Style

Mutakin M, Fauziati R, Fadhilah FN, Zuhrotun A, Amalia R, Hadisaputri YE. Pharmacological Activities of Soursop (Annona muricata Lin.). Molecules. 2022; 27(4):1201. https://doi.org/10.3390/molecules27041201

Chicago/Turabian Style

Mutakin, Mutakin, Rizky Fauziati, Fahrina Nur Fadhilah, Ade Zuhrotun, Riezki Amalia, and Yuni Elsa Hadisaputri. 2022. "Pharmacological Activities of Soursop (Annona muricata Lin.)" Molecules 27, no. 4: 1201. https://doi.org/10.3390/molecules27041201

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