Highly Efficient Micro-Scale Liquid-Liquid In-Flow Extraction of 99mTc from Molybdenum
Abstract
:1. Introduction
2. Results and Discussion
3. Material and Methods
3.1. Materials
- a Zaiput SEP-10 device (purchased by ZAIPUT Flow Technologies company, Cambridge, MA, USA) mounting an OB-100 hydrophobic membrane, supplied with the device;
- two WPX1-U1/16S2-J8-CP peristaltic pumps (WELCO, Tokyo, Japan), flow rate of 0.5 mL/min at 6 V;
- two power supplies;
- a teflon T-junction;
- an ETFE capillary loop (1/8 “, length = 106 cm; internal diameter 1.59 mm; internal volume about 2.1 mL);
- ETFE tubes (1/8 “, internal diameter = 1.59 mm) and connectors.
3.2. Procedure
3.3. Quality Controls
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Sample | Volume [mL] | 99mTc % |
---|---|---|
Sample vial | empty | 3.3 ± 0.7 |
ORG OUT 1 | 4 | - |
AQ OUT 1 | 5 | - |
ORG OUT 2 | 8.5 | 91.0 ± 1.8 |
AQ OUT 2 | 7 | 2.1 ± 0.6 |
ORG OUT 3 | 2.5 | 2.2 ± 1.4 |
AQ OUT 3 | 3 | 1.5 ± 2.1 |
H2O washing | 5 | - |
MEK washing | 5 | - |
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Martini, P.; Uccelli, L.; Duatti, A.; Marvelli, L.; Esposito, J.; Boschi, A. Highly Efficient Micro-Scale Liquid-Liquid In-Flow Extraction of 99mTc from Molybdenum. Molecules 2021, 26, 5699. https://doi.org/10.3390/molecules26185699
Martini P, Uccelli L, Duatti A, Marvelli L, Esposito J, Boschi A. Highly Efficient Micro-Scale Liquid-Liquid In-Flow Extraction of 99mTc from Molybdenum. Molecules. 2021; 26(18):5699. https://doi.org/10.3390/molecules26185699
Chicago/Turabian StyleMartini, Petra, Licia Uccelli, Adriano Duatti, Lorenza Marvelli, Juan Esposito, and Alessandra Boschi. 2021. "Highly Efficient Micro-Scale Liquid-Liquid In-Flow Extraction of 99mTc from Molybdenum" Molecules 26, no. 18: 5699. https://doi.org/10.3390/molecules26185699