A Universal Cassette-Based System for the Dissolution of Solid Targets
Abstract
:1. Introduction
2. Materials and Methods
2.1. Irradiated Targets
2.2. Design of the Reactor Components
2.2.1. Reactor Dissolution Vial
- Borosilicate glass;
- Quartz;
- PEEK.
2.2.2. Vial-Holder and Mounting Rods
2.2.3. Target Holder
2.3. Dissolution Tests
3. Results
3.1. Dissolution Reactor Assembly
3.2. Operational Testing
4. Discussion
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
Sample Availability
References
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Component | Material |
---|---|
Dissolution Vial | quartz; borosilicate glass; PEEK 1 |
Vial-Holder and mounting rods | aluminium alloy 6082; stainless steel |
Target holder | aluminium; copper |
O-ring | NBR 2 70 |
Target | Pellet Mass/Thickness | Irradiation Parameters | Module | Vial Material | Process Parameters |
---|---|---|---|---|---|
NatY on Nb | 0.0758 g 150 μm | 12.5 MeV | Trasis | PEEK | 2 mL HCl 2 M |
10 µA | RT 1 | ||||
5 min | Time 1 h | ||||
NatCr on Au/Cu | 0.02 g 400 μm | 16 MeV | E&Z | Borosilicate glass | 3 mL HCl 8 M |
10 µA | Heating up to 70 °C | ||||
15 min | Time 1 h | ||||
NatMo on Au/Cu | 0.02 g 280 μm | 19 MeV | E&Z | Borosilicate glass | 1.5 mL (×3 times) H2O2 30% |
1 µA | Heating up to 90 °C | ||||
2 min | Time 30 min |
Target | N Test | Target Weight | Difference (g) | Pellet’s Initial Weight (g) | |
---|---|---|---|---|---|
Before Dissolution (g) | After Dissolution (g) | ||||
NatY on Nb | 6 | 6.50 ± 0.04 | 6.43 ± 0.04 | 0.0758 ± 0.0007 | 0.0758 |
NatCr on Au/Cu | 5 | 6.90 ± 0.02 | 6.70 ± 0.02 | 0.200 ± 0.002 | 0.2 |
NatMo on Au/Cu | 3 | 6.86 ± 0.02 | 6.66 ± 0.02 | 0.200 ± 0.002 | 0.2 |
Isotope | Activity @ EOD (MBq) | Activity @ EOB (MBq) | |
---|---|---|---|
Measured | Rescaled | Predicted | |
89Zr | 8.8 | 8.9 | 9.7 |
52Mn | 21 | 22 | 23 |
99mTc | 0.87 | 0.88 | 0.92 |
Backing | Pellet | Desired Isotope | Isotope Produced in the Backing | Half-Life (h) | E (keV) | MDA (Bq) |
---|---|---|---|---|---|---|
Nb | Y | 89Zr | 93mMo | 6.85 | 684.693 | 17.6 |
Cu/Au | Cr | 52Mn | 197mHg | 23.8 | 133.98 | 23.4 |
197gHg | 64.14 | 191.364 | 1843.8 | |||
Cu/Au | Mo | 99mTc | 197mHg | 23.8 | 133.98 | 10.4 |
197gHg | 64.14 | 191.364 | 785.0 |
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Sciacca, G.; Martini, P.; Cisternino, S.; Mou, L.; Amico, J.; Esposito, J.; Gorgoni, G.; Cazzola, E. A Universal Cassette-Based System for the Dissolution of Solid Targets. Molecules 2021, 26, 6255. https://doi.org/10.3390/molecules26206255
Sciacca G, Martini P, Cisternino S, Mou L, Amico J, Esposito J, Gorgoni G, Cazzola E. A Universal Cassette-Based System for the Dissolution of Solid Targets. Molecules. 2021; 26(20):6255. https://doi.org/10.3390/molecules26206255
Chicago/Turabian StyleSciacca, Gabriele, Petra Martini, Sara Cisternino, Liliana Mou, Jonathan Amico, Juan Esposito, Giancarlo Gorgoni, and Emiliano Cazzola. 2021. "A Universal Cassette-Based System for the Dissolution of Solid Targets" Molecules 26, no. 20: 6255. https://doi.org/10.3390/molecules26206255