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Bioaerogels: Promising Nanostructured Materials in Fluid Management, Healing and Regeneration of Wounds

1
Universidade Católica Portuguesa, CBQF-Centro de Biotecnologia e Química Fina–Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal
2
Department of Pharmacology, Pharmacy and Pharmaceutical Technology, I+D Farma Group (GI-1645), Faculty of Pharmacy and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, Spain
3
Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, I-84084 Fisciano, Italy
4
Center for Interdisciplinary Research in Health, Institute of Health Sciences, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal
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Instituto de Investigação e Inovação em Saúde, Universidade do Porto (i3S), 4200-135 Porto, Portugal
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Biochemistry Unit, Department of Biomedicine, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal
7
Escola Superior de Saúde, Instituto Politécnico do Porto, 4200-072 Porto, Portugal
*
Authors to whom correspondence should be addressed.
Academic Editors: Gaëlle Fontaine and David Mills
Molecules 2021, 26(13), 3834; https://doi.org/10.3390/molecules26133834
Received: 5 May 2021 / Revised: 9 June 2021 / Accepted: 21 June 2021 / Published: 23 June 2021
Wounds affect one’s quality of life and should be managed on a patient-specific approach, based on the particular healing phase and wound condition. During wound healing, exudate is produced as a natural response towards healing. However, excessive production can be detrimental, representing a challenge for wound management. The design and development of new healing devices and therapeutics with improved performance is a constant demand from the healthcare services. Aerogels can combine high porosity and low density with the adequate fluid interaction and drug loading capacity, to establish hemostasis and promote the healing and regeneration of exudative and chronic wounds. Bio-based aerogels, i.e., those produced from natural polymers, are particularly attractive since they encompass their intrinsic chemical properties and the physical features of their nanostructure. In this work, the emerging research on aerogels for wound treatment is reviewed for the first time. The current scenario and the opportunities provided by aerogels in the form of films, membranes and particles are identified to face current unmet demands in fluid managing and wound healing and regeneration. View Full-Text
Keywords: aerogels; biopolymer; exudate; wound healing aerogels; biopolymer; exudate; wound healing
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MDPI and ACS Style

Bernardes, B.G.; Del Gaudio, P.; Alves, P.; Costa, R.; García-Gonzaléz, C.A.; Oliveira, A.L. Bioaerogels: Promising Nanostructured Materials in Fluid Management, Healing and Regeneration of Wounds. Molecules 2021, 26, 3834. https://doi.org/10.3390/molecules26133834

AMA Style

Bernardes BG, Del Gaudio P, Alves P, Costa R, García-Gonzaléz CA, Oliveira AL. Bioaerogels: Promising Nanostructured Materials in Fluid Management, Healing and Regeneration of Wounds. Molecules. 2021; 26(13):3834. https://doi.org/10.3390/molecules26133834

Chicago/Turabian Style

Bernardes, Beatriz G., Pasquale Del Gaudio, Paulo Alves, Raquel Costa, Carlos A. García-Gonzaléz, and Ana Leite Oliveira. 2021. "Bioaerogels: Promising Nanostructured Materials in Fluid Management, Healing and Regeneration of Wounds" Molecules 26, no. 13: 3834. https://doi.org/10.3390/molecules26133834

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