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Valorization of Yarrow (Achillea millefolium L.) By-Product through Application of Subcritical Water Extraction

1
Faculty of Technology, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia
2
Faculty of Food Technology, J. J. Strossmayer University of Osijek, Cara Hadrijana 10E, 31000 Osijek, Croatia
3
Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovica 8, 21000 Novi Sad, Serbia
*
Author to whom correspondence should be addressed.
Academic Editor: Yu Yang
Molecules 2020, 25(8), 1878; https://doi.org/10.3390/molecules25081878
Received: 20 March 2020 / Revised: 14 April 2020 / Accepted: 15 April 2020 / Published: 18 April 2020
(This article belongs to the Special Issue Subcritical Water Extraction of Bioactive Compounds)
In the present study, valorization of yarrow (Achillea millefolium) by-product from the filter tea industry was investigated through the application of subcritical water for the extraction of bioactive compounds. The influence of different process parameters (temperature 120–200 °C, extraction time 10–30 min, and HCl concentration in extraction solvent 0–1.5%) on extract quality in terms of content of bioactive compounds and antioxidant activity was investigated. Optimal conditions of the extraction process (temperature 198 °C, extraction time 16.5 min, and without acidifer) were determined and, when applied, the most efficient exploitation of by-products is achieved, that is, attainment of extracts rich in total phenols and flavonoids and high antioxidant activity. In addition, by applying the high performance liquid chromatographic analysis, the content of chlorogenic acid was determined as well as the hydroxymethylfurfural content in obtained extracts. The results demonstrated that subcritical water can be successfully used for utilization of yarrow by-products for obtaining extracts rich in antioxidants. View Full-Text
Keywords: Achillea millefolium; yarrow; subcritical water; polyphenols; antioxidant activity; optimization Achillea millefolium; yarrow; subcritical water; polyphenols; antioxidant activity; optimization
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MDPI and ACS Style

Vladić, J.; Jakovljević, M.; Molnar, M.; Vidović, S.; Tomić, M.; Drinić, Z.; Jokić, S. Valorization of Yarrow (Achillea millefolium L.) By-Product through Application of Subcritical Water Extraction. Molecules 2020, 25, 1878.

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