Advances of Anti-Caries Nanomaterials
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu 610041, China
Department of Operative Dentistry and Endodontics, Sichuan University, Chengdu 610041, China
Department of Operative Dentistry and Endodontics, Guanghua School of Stomatology and Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou 510055, China
Authors to whom correspondence should be addressed.
Academic Editors: Giuseppe Cirillo and Hom Nath Dhakal
Molecules 2020, 25(21), 5047; https://doi.org/10.3390/molecules25215047
Received: 3 September 2020 / Revised: 25 October 2020 / Accepted: 27 October 2020 / Published: 30 October 2020
(This article belongs to the Special Issue 25th Anniversary of Molecules—Recent Advances in Materials Chemistry)
Caries is the most common and extensive oral chronic disease. Due to the lack of anti-caries properties, traditional caries filling materials can easily cause secondary caries and lead to treatment failure. Nanomaterials can interfere with the bacteria metabolism, inhibit the formation of biofilm, reduce demineralization, and promote remineralization, which is expected to be an effective strategy for caries management. The nanotechnology in anti-caries materials, especially nano-adhesive and nano-composite resin, has developed fast in recent years. In this review, the antibacterial nanomaterials, remineralization nanomaterials, and nano-drug delivery systems are reviewed. We are aimed to provide a theoretical basis for the future development of anti-caries nanomaterials.