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Polyphenols and Other Bioactive Compounds of Sideritis Plants and Their Potential Biological Activity

1
Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland
2
Faculty of Health Sciences, Medical University of Lodz, 90-647 Lodz, Poland
*
Author to whom correspondence should be addressed.
Academic Editor: De-Xing Hou
Molecules 2020, 25(16), 3763; https://doi.org/10.3390/molecules25163763
Received: 3 July 2020 / Revised: 11 August 2020 / Accepted: 13 August 2020 / Published: 18 August 2020
(This article belongs to the Special Issue Plant Polyphenols and Gut Health)
Due to the growing problem of obesity associated with type 2 diabetes and cardiovascular diseases, causes of obesity are extensively investigated. In addition to a high caloric diet and low physical activity, gut microbiota disturbance may have a potential impact on excessive weight gain. Some reports indicate differences in the composition of the intestinal microflora of obese people in comparison to lean. Bioactive compounds of natural origin with beneficial and multifaceted effects on the body are more frequently used in prevention and treatment of many metabolic diseases including obesity. Sideritis scardica is traditionally consumed as mountain tea in the Balkans to strengthen the body and improve mood. Many reports indicate a positive effect on digestive system, weight loss, and prevention of insulin resistance. Additionally, it exhibits antioxidant activity and anti-inflammatory effects. The positive effect of Sideritis scardica extracts on memory and general cognitive abilities is indicated as well. The multilevel positive effect on the body appears to originate from the abundant occurrence of phenolic compounds, especially phenolic acids in Sideritis scardica extracts. However, mechanisms underlying their action require careful discussion and further research. Therefore, the objective of this review is to summarize the available knowledge on the role and mechanism of action of biologically active compounds of Sideritis scardica and other related species from the genus Sideritis. View Full-Text
Keywords: Sideritis scardica; polyphenols; biological active compounds; gut microbiota; antioxidant; anti-inflammatory and neuroprotective properties Sideritis scardica; polyphenols; biological active compounds; gut microbiota; antioxidant; anti-inflammatory and neuroprotective properties
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MDPI and ACS Style

Żyżelewicz, D.; Kulbat-Warycha, K.; Oracz, J.; Żyżelewicz, K. Polyphenols and Other Bioactive Compounds of Sideritis Plants and Their Potential Biological Activity. Molecules 2020, 25, 3763. https://doi.org/10.3390/molecules25163763

AMA Style

Żyżelewicz D, Kulbat-Warycha K, Oracz J, Żyżelewicz K. Polyphenols and Other Bioactive Compounds of Sideritis Plants and Their Potential Biological Activity. Molecules. 2020; 25(16):3763. https://doi.org/10.3390/molecules25163763

Chicago/Turabian Style

Żyżelewicz, Dorota, Kamila Kulbat-Warycha, Joanna Oracz, and Kacper Żyżelewicz. 2020. "Polyphenols and Other Bioactive Compounds of Sideritis Plants and Their Potential Biological Activity" Molecules 25, no. 16: 3763. https://doi.org/10.3390/molecules25163763

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