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Open AccessArticle

Lignin Modification Supported by DFT-Based Theoretical Study as a Way to Produce Competitive Natural Antioxidants

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Latvian State Institute of Wood Chemistry, Dzerbenes Str. 27, LV-1006 Riga, Latvia
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INSERM UMR 1248, Université de Limoges, Faculté de Pharmacie, 2 rue du Docteur Marcland, 87025 Limoges Cedex, France
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CICECO/University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal
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Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University, tř. 17 listopadu 12, 771 46 Olomouc, Czech Republic
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Authors to whom correspondence should be addressed.
Molecules 2019, 24(9), 1794; https://doi.org/10.3390/molecules24091794
Received: 9 April 2019 / Revised: 4 May 2019 / Accepted: 8 May 2019 / Published: 9 May 2019
(This article belongs to the Section Green Chemistry)
The valorization of lignins as renewable aromatic feedstock is of utmost importance in terms of the use of sustainable resources. This study provides a deductive approach towards market-oriented lignin-derived antioxidants by ascertaining the direct effect of different structural features of lignin on the reactivity of its phenolic OH groups in the radical scavenging reactions. The antioxidant activity of a series of compounds, modeling lignin structural units, was experimentally characterized and rationalized, using thermodynamic descriptors. The calculated O–H bond dissociation enthalpies (BDE) of characteristic lignin subunits were used to predict the modification pathways of technical lignins. The last ones were isolated by soda delignification from different biomass sources and their oligomeric fractions were studied as a raw material for modification and production of optimized antioxidants. These were characterized in terms of chemical structure, molecular weight distribution, content of the functional groups, and the antioxidant activity. The developed approach for the targeted modification of lignins allowed the products competitive with two commercial synthetic phenolic antioxidants in both free radical scavenging and stabilization of thermooxidative destruction of polyurethane films. View Full-Text
Keywords: lignins; antioxidant activity; molecular rationalization; modification; stabilizers for polymers lignins; antioxidant activity; molecular rationalization; modification; stabilizers for polymers
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MDPI and ACS Style

Lauberte, L.; Fabre, G.; Ponomarenko, J.; Dizhbite, T.; Evtuguin, D.V.; Telysheva, G.; Trouillas, P. Lignin Modification Supported by DFT-Based Theoretical Study as a Way to Produce Competitive Natural Antioxidants. Molecules 2019, 24, 1794.

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