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Curcumin: Total-Scale Analysis of the Scientific Literature

Oral and Maxillofacial Radiology, Applied Oral Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China
Warsaw University of Life Sciences, Faculty of Applied Informatics and Mathematics, 02-787 Warsaw, Poland
Institute of Molecular Biology “Roumen Tsanev”, Department of Biochemical Pharmacology and Drug Design, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 21, 1113 Sofia, Bulgaria
Pharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany
Department of Pharmaceutical Botany, “Iuliu Haţieganu” University of Medicine and Pharmacy, 23 Ghe. Marinescu Street, 400337 Cluj-Napoca, Romania
Laboratory of Chromatography, Institute of Advanced Horticulture Research of Transylvania, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania
Department of Pharmacy, University “G. d’Annunzio” of Chieti-Pescara, Via dei Vestini 31,66100 Chieti, Italy
School of Pharmacy, University of Camerino, 62032 Camerino, Italy
The Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzębiec, 05-552 Magdalenka, Poland
Department of Agronomy, Food, Natural Resources, Animals and Environment (DAFNAE), Agripolis Campus, University of Padova, 35020 Padova, Italy
Department of Pharmaceutical and Pharmacological Sciences University of Padova, 35020 Padova, Italy
Department of Food Science & Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China
Department of Behavioral Neurobiology, Institute of Neurobiology, Bulgarian Academy of Sciences, 1000 Sofia, Bulgaria
GLOBE Program Association (GLOBE-PA), Grandville, MI, USA
MEDFUTURE - Research Center for Advanced Medicine, 400037 Cluj-Napoca, Romania
Research Center for Functional Genomics, Biomedicine and Translational Medicine, Institute of Doctoral Studies, “Iuliu Hatieganu” University of Medicine and Pharmacy, 400037 Cluj-Napoca, Romania
Department of Experimental Pathology, “Prof. Dr. Ion Chiricuta”, The Oncology Institute, 400037 Cluj-Napoca, Romania
The National Institute of Poultry Husbandry, Harper Adams University, Shropshire TF10 8NB, UK
Department of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Palackého tř. 1946/1, 612 42 Brno, Czech Republic
Department of Pharmacognosy, University of Vienna, 1090 Vienna, Austria
Authors to whom correspondence should be addressed.
Molecules 2019, 24(7), 1393;
Received: 1 March 2019 / Revised: 6 April 2019 / Accepted: 7 April 2019 / Published: 9 April 2019
(This article belongs to the Special Issue Bioactive Molecules and Their Mechanisms of Action)
PDF [1990 KB, uploaded 9 April 2019]


The current study aimed to provide a comprehensive bibliometric overview of the literature on curcumin, complementing the previous reviews and meta-analyses on its potential health benefits. Bibliometric data for the current analysis were extracted from the Web of Science Core Collection database, using the search string TOPIC=(“curcumin*”), and analyzed by the VOSviewer software. The search yielded 18,036 manuscripts. The ratio of original articles to reviews was 10.4:1. More than half of the papers have been published since 2014. The major contributing countries were the United States, China, India, Japan, and South Korea. These publications were mainly published in journals representing the following scientific disciplines: biochemistry, chemistry, oncology, and pharmacology. There was a significant positive correlation between the total publication count and averaged citations per manuscript for affiliations, but not for countries/regions and journals. Chemicals that were frequently mentioned in the keywords of evaluated curcumin publications included curcuminoids, resveratrol, chitosan, flavonoids, quercetin, and polyphenols. The literature mainly focused on curcumin’s effects against cancer, inflammation, and oxidative stress. Cancer types most frequently investigated were breast, colon, colorectal, pancreatic, and prostate cancers. View Full-Text
Keywords: curcumin; pharmacology; bibliometrics; biochemistry; cancer; citation analysis; VOSviewer; Web of Science curcumin; pharmacology; bibliometrics; biochemistry; cancer; citation analysis; VOSviewer; Web of Science

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Yeung, A.W.K.; Horbańczuk, M.; Tzvetkov, N.T.; Mocan, A.; Carradori, S.; Maggi, F.; Marchewka, J.; Sut, S.; Dall’Acqua, S.; Gan, R.-Y.; Tancheva, L.P.; Polgar, T.; Berindan-Neagoe, I.; Pirgozliev, V.; Šmejkal, K.; Atanasov, A.G. Curcumin: Total-Scale Analysis of the Scientific Literature. Molecules 2019, 24, 1393.

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