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Polyphenols, Antioxidant, Antibacterial, and Biofilm Inhibitory Activities of Peel and Pulp of Citrus medica L., Citrus bergamia, and Citrus medica cv. Salò Cultivated in Southern Italy

1
Istituto di Scienze dell’Alimentazione, Consiglio Nazionale delle Ricerche (ISA-CNR), via Roma 64, 83100 Avellino, Italy
2
Department of Agricultural, Environmental and Food Sciences, DiAAA-University of Molise, Via de Sanctis s.n.c., 83100 Campobasso, Italy
3
Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano (Salerno), Italy
*
Authors to whom correspondence should be addressed.
Academic Editors: Paola Di Donato and Brigida Silvestri
Molecules 2019, 24(24), 4577; https://doi.org/10.3390/molecules24244577
Received: 19 November 2019 / Revised: 10 December 2019 / Accepted: 11 December 2019 / Published: 13 December 2019
The aim of this paper was to study the polyphenols of peel and pulp of three Citrus taxa—Citrus medica, Citrus bergamia, and Citrus medica cv. Salò—cultivated in the Cosenza province, Southern Italy, and to evaluate their antioxidant and antibacterial activity, performed against Escherichia coli, Listeria monocytogenes, Pseudomonas aeruginosa, Staphylococcus aureus, and Pectobacterium carotovorum. Furthermore, we assessed the inhibitory effect of the extracts on bacterial capacity to form biofilm, and on the metabolic activity of the cells present therein. The results indicated that such extracts could find new potential applications in the field of natural antioxidant and anti-bacterial agents in pharmaceutics, agriculture, and food fields. View Full-Text
Keywords: Citrus medica; Citrus bergamia; Citrus medica cv. Salò; polyphenols; biofilm; antibacterial activity Citrus medica; Citrus bergamia; Citrus medica cv. Salò; polyphenols; biofilm; antibacterial activity
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MDPI and ACS Style

Fratianni, F.; Cozzolino, A.; De Feo, V.; Coppola, R.; Ombra, M.N.; Nazzaro, F. Polyphenols, Antioxidant, Antibacterial, and Biofilm Inhibitory Activities of Peel and Pulp of Citrus medica L., Citrus bergamia, and Citrus medica cv. Salò Cultivated in Southern Italy. Molecules 2019, 24, 4577.

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