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The Potential Use of Resveratrol for Cancer Prevention

Team OCS, Institute of Molecular Chemistry of University of Burgundy (ICMUB UMR CNRS 6302), Univ. Bourgogne Franche-Comté, 21000 Dijon, France
Team Bio-PeroxIL, “Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism” (EA7270)/Univ. Bourgogne Franche-Comté/Inserm, 21000 Dijon, France
Author to whom correspondence should be addressed.
Molecules 2019, 24(24), 4506;
Received: 30 September 2019 / Revised: 20 November 2019 / Accepted: 5 December 2019 / Published: 9 December 2019
(This article belongs to the Special Issue Resveratrol: From the Farm to the Clinic)
In addition to the traditional treatments of cancer and cancer prevention, the use of natural compounds, especially those found in food, should be considered. To clarify if resveratrol has the potential for cancer prevention and the possibility of use in therapy, the following must be taken into account: data from epidemiology, clinical protocol (case and control), preclinical studies (lab animals), use of established cell lines as models of cancer cells, test tube assays (enzymes activities), and requirements of nanotechnologies in order to discover new drugs to fight cancer. From this perspective and future expected advances, more information is needed such as improved efficacy, methods of application, and the synergistic sensitization of resveratrol as an adjuvant. In addition, resveratrol nanoformulation is considered to overcome its weak bioavailability. View Full-Text
Keywords: cancer; prevention; resveratrol; approach strategies; mechanisms; innovative formulations cancer; prevention; resveratrol; approach strategies; mechanisms; innovative formulations
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Vervandier-Fasseur, D.; Latruffe, N. The Potential Use of Resveratrol for Cancer Prevention. Molecules 2019, 24, 4506.

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