Radiation Induced One-Electron Oxidation of 2-Thiouracil in Aqueous Solutions
Abstract
:1. Introduction
2. Results
2.1. Oxidation by ●OH Radicals—Influence of 2-TU Concentration on Absorption Spectra
2.1.1. Time Evolution of Absorption Spectra—Low Concentration of 2-TU
2.1.2. Time Evolution of Absorption Spectra—High Concentration of 2-TU
2.1.3. Influence of pH on Time Evolution of Absorption Spectra at Low and High Concentration of 2-TU
2.2. Oxidation by ●OH Radicals—Kinetics
2.2.1. The Rate Constant of the ●OH Reaction with 2-TU
2.2.2. Equilibrium Constant and Rate Constants of Reactions Involved in Equilibrium
2.3. Oxidation by ●OH Radicals—Time-Resolved Conductivity
2.4. Oxidation by ●N3 Radicals and CH3CN●+ Radical Cations
2.5. Theoretical Calculations
3. Discussion
3.1. Assignment of the Absorption Spectra to Respective Intermediates
3.2. Justification of the Reaction Pathway Involving Hemibonded ●OH Adducts to Sulfur Atom
3.3. Mechanisms of ●OH and ●N3-Induced Oxidation of 2-Thiouracil
4. Materials and Methods
4.1. Chemicals
4.2. Preparation of Solutions
4.3. Pulse Radiolysis
4.4. Theoretical Procedures
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Sample Availability: Samples of the 2-thiouracil are available from the authors. |
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Skotnicki, K.; Taras-Goslinska, K.; Janik, I.; Bobrowski, K. Radiation Induced One-Electron Oxidation of 2-Thiouracil in Aqueous Solutions. Molecules 2019, 24, 4402. https://doi.org/10.3390/molecules24234402
Skotnicki K, Taras-Goslinska K, Janik I, Bobrowski K. Radiation Induced One-Electron Oxidation of 2-Thiouracil in Aqueous Solutions. Molecules. 2019; 24(23):4402. https://doi.org/10.3390/molecules24234402
Chicago/Turabian StyleSkotnicki, Konrad, Katarzyna Taras-Goslinska, Ireneusz Janik, and Krzysztof Bobrowski. 2019. "Radiation Induced One-Electron Oxidation of 2-Thiouracil in Aqueous Solutions" Molecules 24, no. 23: 4402. https://doi.org/10.3390/molecules24234402