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Review

Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity

1
Department of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Palackého tř. 1, 61242 Brno, Czech Republic
2
Department of Molecular Biology and Pharmaceutical Biotechnology, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Palackého tř. 1, 61242 Brno, Czech Republic
3
Department of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamýcká 129, 16500 Praha-Suchdol, Czech Republic
4
Department of Medical Biology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 03601 Martin, Slovakia
*
Author to whom correspondence should be addressed.
Molecules 2019, 24(12), 2288; https://doi.org/10.3390/molecules24122288
Received: 31 May 2019 / Accepted: 18 June 2019 / Published: 20 June 2019
(This article belongs to the Special Issue Bioactive Molecules and Their Mechanisms of Action)
Maytenus macrocarpa (Celastraceae) is a tree native to Amazonia. Its roots, leaves, bark, and combinations of these are used in traditional medicine mainly to treat rheumatism and, to a lesser extent, to heal wounds and to combat bronchitis and diarrhea. To date, mainly triterpenes and dihydro-β-agarofuran sesquiterpenes were isolated from M. macrocarpa. Extracts and selected pure compounds isolated from the leaves, roots, and stem bark showed antibacterial, antiviral, antiparasitic, anti-inflammatory, and cytotoxic activities in vitro. The aim of this review is to summarize the available ethnobotanical, phytochemical, and pharmacological information about this traditional Amazonian medicinal tree, as well as to attract the attention of phytochemists and pharmacognosists to this potentially interesting source of ethnopharmaceuticals. View Full-Text
Keywords: dihydro-β-agarofuran sesquiterpene; folk medicine; Maytenus macrocarpa; rheumatism; triterpene dihydro-β-agarofuran sesquiterpene; folk medicine; Maytenus macrocarpa; rheumatism; triterpene
MDPI and ACS Style

Malaník, M.; Treml, J.; Rjašková, V.; Tížková, K.; Kaucká, P.; Kokoška, L.; Kubatka, P.; Šmejkal, K. Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity. Molecules 2019, 24, 2288. https://doi.org/10.3390/molecules24122288

AMA Style

Malaník M, Treml J, Rjašková V, Tížková K, Kaucká P, Kokoška L, Kubatka P, Šmejkal K. Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity. Molecules. 2019; 24(12):2288. https://doi.org/10.3390/molecules24122288

Chicago/Turabian Style

Malaník, Milan, Jakub Treml, Veronika Rjašková, Karolina Tížková, Petra Kaucká, Ladislav Kokoška, Peter Kubatka, and Karel Šmejkal. 2019. "Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity" Molecules 24, no. 12: 2288. https://doi.org/10.3390/molecules24122288

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