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Keywords = Maytenus macrocarpa

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22 pages, 3431 KB  
Review
Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity
by Milan Malaník, Jakub Treml, Veronika Rjašková, Karolina Tížková, Petra Kaucká, Ladislav Kokoška, Peter Kubatka and Karel Šmejkal
Molecules 2019, 24(12), 2288; https://doi.org/10.3390/molecules24122288 - 20 Jun 2019
Cited by 13 | Viewed by 6869
Abstract
Maytenus macrocarpa (Celastraceae) is a tree native to Amazonia. Its roots, leaves, bark, and combinations of these are used in traditional medicine mainly to treat rheumatism and, to a lesser extent, to heal wounds and to combat bronchitis and diarrhea. To date, mainly [...] Read more.
Maytenus macrocarpa (Celastraceae) is a tree native to Amazonia. Its roots, leaves, bark, and combinations of these are used in traditional medicine mainly to treat rheumatism and, to a lesser extent, to heal wounds and to combat bronchitis and diarrhea. To date, mainly triterpenes and dihydro-β-agarofuran sesquiterpenes were isolated from M. macrocarpa. Extracts and selected pure compounds isolated from the leaves, roots, and stem bark showed antibacterial, antiviral, antiparasitic, anti-inflammatory, and cytotoxic activities in vitro. The aim of this review is to summarize the available ethnobotanical, phytochemical, and pharmacological information about this traditional Amazonian medicinal tree, as well as to attract the attention of phytochemists and pharmacognosists to this potentially interesting source of ethnopharmaceuticals. Full article
(This article belongs to the Special Issue Bioactive Molecules and Their Mechanisms of Action)
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