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Molecules 2018, 23(5), 1189; https://doi.org/10.3390/molecules23051189

Antioxidant and ACE Inhibitory Activity of Enzymatic Hydrolysates from Ruditapes philippinarum

1
School of Food Science and Technology, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, China
2
Department of Food Science and Engineering, Harbin Institute of Technology, Harbin 150090, China
*
Author to whom correspondence should be addressed.
Academic Editor: Nicola Marchetti
Received: 13 April 2018 / Revised: 3 May 2018 / Accepted: 8 May 2018 / Published: 16 May 2018
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Abstract

Ruditapes philippinarum proteins were hydrolyzed by trypsin, neutrase, and pepsin. The antioxidant activities and ACE inhibitory activity of hydrolysates were analyzed and the antioxidant activities were related to their molecular weight distribution and amino acid compositions. Results indicated the hydrolysis of proteins led to an increase in small peptides and free amino acids. The antioxidant activities of Ruditapes philippinarum hydrolysates against DPPH radical scavenging, inhibition on linoleic acid peroxidation, and reducing power showed that the neutrase hydrolysate exhibited the strongest antioxidant activity. In addition, an ACE inhibition assay revealed that the pepsin hydrolysate had the highest ACE inhibitory ability. Ruditapes philippinarum protein hydrolysates could be a promising source of natural antioxidant and ACE inhibitory. View Full-Text
Keywords: Ruditapes philippinarum; hydrolysates; molecular weight distribution; amino acid composition; antioxidant activity; ACE inhibitory Ruditapes philippinarum; hydrolysates; molecular weight distribution; amino acid composition; antioxidant activity; ACE inhibitory
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Yu, Y.; Fan, F.; Wu, D.; Yu, C.; Wang, Z.; Du, M. Antioxidant and ACE Inhibitory Activity of Enzymatic Hydrolysates from Ruditapes philippinarum. Molecules 2018, 23, 1189.

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