Next Article in Journal
Theoretical Study of ClOO + NO Reaction: Mechanism and Kinetics
Next Article in Special Issue
Preparation, Characterization, and Biological Activities of Topical Anti-Aging Ingredients in a Citrus junos Callus Extract
Previous Article in Journal
Anti-Proliferative Activity of Triterpenoids and Sterols Isolated from Alstonia scholaris against Non-Small-Cell Lung Carcinoma Cells
Previous Article in Special Issue
Resveratrol-Induced Effects on Body Fat Differ Depending on Feeding Conditions
Open AccessArticle

Optimization of Bioactive Polyphenols Extraction from Picea Mariana Bark

Renewable Materials Research Centre, Department of Wood and Forest Sciences, Université Laval, Québec, QC G1V 0A6, Canada
Institute of Nutrition and Functional Food (INAF), Université Laval, Quebec, QC G1V 0A6, Canada
Author to whom correspondence should be addressed.
Molecules 2017, 22(12), 2118;
Received: 30 October 2017 / Revised: 30 November 2017 / Accepted: 30 November 2017 / Published: 1 December 2017
(This article belongs to the Collection Bioactive Compounds)
Reported for its antioxidant, anti-inflammatory and non-toxicity properties, the hot water extract of Picea mariana bark was demonstrated to contain highly valuable bioactive polyphenols. In order to improve the recovery of these molecules, an optimization of the extraction was performed using water. Several extraction parameters were tested and extracts obtained analyzed both in terms of relative amounts of different phytochemical families and of individual molecules concentrations. As a result, low temperature (80 °C) and low ratio of bark/water (50 mg/mL) were determined to be the best parameters for an efficient polyphenol extraction and that especially for low molecular mass polyphenols. These were identified as stilbene monomers and derivatives, mainly stilbene glucoside isorhapontin (up to 12.0% of the dry extract), astringin (up to 4.6%), resveratrol (up to 0.3%), isorhapontigenin (up to 3.7%) and resveratrol glucoside piceid (up to 3.1%) which is here reported for the first time for Picea mariana. New stilbene derivatives, piceasides O and P were also characterized herein as new isorhapontin dimers. This study provides novel information about the optimal extraction of polyphenols from black spruce bark, especially for highly bioactive stilbenes including the trans-resveratrol. View Full-Text
Keywords: Picea mariana; bark; hot water extraction; chemometrics; stilbenes; piceaside Picea mariana; bark; hot water extraction; chemometrics; stilbenes; piceaside
Show Figures

Graphical abstract

MDPI and ACS Style

Francezon, N.; Meda, N.-S.-B.; Stevanovic, T. Optimization of Bioactive Polyphenols Extraction from Picea Mariana Bark. Molecules 2017, 22, 2118.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Search more from Scilit
Back to TopTop