Next Article in Journal
Resveratrol-Induced Effects on Body Fat Differ Depending on Feeding Conditions
Next Article in Special Issue
Gold-Catalyzed Addition of β-Ketoesters to Alkenes: Influence of Electronic and Steric Effects in the Reaction Outcome
Previous Article in Journal
Trend in H2S Biology and Medicine Research—A Bibliometric Analysis
Open AccessArticle

Platinum-Catalyzed Allylation of 2,3-Disubstituted Indoles with Allylic Acetates

1
School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan
2
Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan
3
Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan
*
Author to whom correspondence should be addressed.
Molecules 2017, 22(12), 2097; https://doi.org/10.3390/molecules22122097
Received: 20 October 2017 / Revised: 24 November 2017 / Accepted: 28 November 2017 / Published: 29 November 2017
(This article belongs to the Special Issue Organometallic Catalysis in Organic Synthesis)
Given the importance of heterocycle indole derivatives, much effort has been directed toward the development of methods for functionalization of the indole nucleus at N1 and C3 sites. Moreover, the platinum-catalyzed allyation of nucleophiles was an established and efficient way, which has been applied to medicinal and organic chemistry. In our research, the platinum-catalyzed 2,3-disubstitued indoles with allylic acetates was investigated under different conditions. Herein, we established a simple, convenient, and efficient method, which afforded high yield of allylated indoles. View Full-Text
Keywords: platinum-catalyzed; indole derivatives; allylic acetates; allylation platinum-catalyzed; indole derivatives; allylic acetates; allylation
Show Figures

Graphical abstract

MDPI and ACS Style

Peng, B.-J.; Wu, W.-T.; Yang, S.-C. Platinum-Catalyzed Allylation of 2,3-Disubstituted Indoles with Allylic Acetates. Molecules 2017, 22, 2097.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop