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Molecules 2017, 22(1), 143;

Identification of Phenolic Compounds from Hancornia speciosa (Apocynaceae) Leaves by UHPLC Orbitrap-HRMS

Departamento de Ciências Farmacêuticas, Universidade Federal da Paraíba, João Pessoa 58051-900, Brazil
Dept. Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, Halle 06120, Germany
Departamento de Farmácia, Universidade Federal do Rio Grande do Norte, Natal 59010-180, Brazil
These authors contributed equally to this paper.
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 23 November 2016 / Revised: 12 January 2017 / Accepted: 13 January 2017 / Published: 15 January 2017
(This article belongs to the Section Natural Products Chemistry)
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Apocynaceae is a botanical family distributed mainly in tropical and subtropical regions of the world. In Brazil, they comprise about 90 genera and 850 species, inhabiting various types of vegetation. Within this large botanical family, the genus Hancornia is considered monotypic, with its only species Hancornia speciosa Gomes. Antihypertensive, antidiabetic, and antiviral activities are described for this species. Despite having been the target of some studies, knowledge of its chemical composition is still limited. In this study, the phenolics of H. speciosa leaves were analyzed using ultra-high performance liquid chromatography (UHPLC) coupled to Orbitrap high-resolution mass spectrometry (HRMS). As a result, 14 compounds were identified viz. protocatechuic acid, catechin, and quercetin, and another 14 were putatively identified viz. B- and C-type procyanidins, while just one compound remained unknown. From the identified compounds, 17 are reported for the first time viz. coumaroylquinic acid isomers and eriodyctiol. The results show that Hancornia speciosa can serve as source of valuable phenolics. View Full-Text
Keywords: Hancornia speciosa; mangabeira; UHPLC; Orbitrap; chemical composition; phenolic compounds Hancornia speciosa; mangabeira; UHPLC; Orbitrap; chemical composition; phenolic compounds

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Bastos, K.X.; Dias, C.N.; Nascimento, Y.M.; da Silva, M.S.; Langassner, S.M.Z.; Wessjohann, L.A.; Tavares, J.F. Identification of Phenolic Compounds from Hancornia speciosa (Apocynaceae) Leaves by UHPLC Orbitrap-HRMS. Molecules 2017, 22, 143.

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