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Open AccessCommunication

Atom-Economic Synthesis of 4-Pyrones from Diynones and Water

College of Pharmacy, Guilin Medical University, Guilin 541004, China
State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, China
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Georgiy B. Shul’pin
Molecules 2017, 22(1), 109;
Received: 21 December 2016 / Revised: 5 January 2017 / Accepted: 5 January 2017 / Published: 10 January 2017
(This article belongs to the Special Issue Reactions of Hydrocarbons and other C‒H Compounds)
Transition-metal-free synthesis of 4-pyrones via TfOH-promoted nucleophilic addition/cyclization of diynones and water has been developed. This transformation is simple, atom economical and environmentally benign, providing rapid and efficient access to substituted 4-pyrones. View Full-Text
Keywords: 4-pyrones; diynones; water; transition-metal-free 4-pyrones; diynones; water; transition-metal-free
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MDPI and ACS Style

Xu, Y.-L.; Teng, Q.-H.; Tong, W.; Wang, H.-S.; Pan, Y.-M.; Ma, X.-L. Atom-Economic Synthesis of 4-Pyrones from Diynones and Water. Molecules 2017, 22, 109.

AMA Style

Xu Y-L, Teng Q-H, Tong W, Wang H-S, Pan Y-M, Ma X-L. Atom-Economic Synthesis of 4-Pyrones from Diynones and Water. Molecules. 2017; 22(1):109.

Chicago/Turabian Style

Xu, Yan-Li; Teng, Qing-Hu; Tong, Wei; Wang, Heng-Shan; Pan, Ying-Ming; Ma, Xian-Li. 2017. "Atom-Economic Synthesis of 4-Pyrones from Diynones and Water" Molecules 22, no. 1: 109.

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