Molecules 2017, 22(1), 109; https://doi.org/10.3390/molecules22010109
Atom-Economic Synthesis of 4-Pyrones from Diynones and Water
1
College of Pharmacy, Guilin Medical University, Guilin 541004, China
2
State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, China
†
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Academic Editor: Georgiy B. Shul’pin
Received: 21 December 2016 / Revised: 5 January 2017 / Accepted: 5 January 2017 / Published: 10 January 2017
(This article belongs to the Special Issue Reactions of Hydrocarbons and other C‒H Compounds)
Abstract
Transition-metal-free synthesis of 4-pyrones via TfOH-promoted nucleophilic addition/cyclization of diynones and water has been developed. This transformation is simple, atom economical and environmentally benign, providing rapid and efficient access to substituted 4-pyrones. View Full-TextKeywords:
4-pyrones; diynones; water; transition-metal-free
▼
Figures
Graphical abstract
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
Share & Cite This Article
MDPI and ACS Style
Xu, Y.-L.; Teng, Q.-H.; Tong, W.; Wang, H.-S.; Pan, Y.-M.; Ma, X.-L. Atom-Economic Synthesis of 4-Pyrones from Diynones and Water. Molecules 2017, 22, 109.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.
Related Articles
Article Metrics
Comments
[Return to top]
Molecules
EISSN 1420-3049
Published by MDPI AG, Basel, Switzerland
RSS
E-Mail Table of Contents Alert