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Molecules 2016, 21(7), 918;

Exploring Flow Procedures for Diazonium Formation

Department of Chemistry, University of Durham, South Road, Durham DH1 3LE, UK
Author to whom correspondence should be addressed.
Academic Editor: Alessandro Palmieri
Received: 12 June 2016 / Revised: 29 June 2016 / Accepted: 5 July 2016 / Published: 14 July 2016
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The synthesis of diazonium salts is historically an important transformation extensively utilized in dye manufacture. However the highly reactive nature of the diazonium functionality has additionally led to the development of many new reactions including several carbon-carbon bond forming processes. It is therefore highly desirable to determine optimum conditions for the formation of diazonium compounds utilizing the latest processing tools such as flow chemistry to take advantage of the increased safety and continuous manufacturing capabilities. Herein we report a series of flow-based procedures to prepare diazonium salts for subsequent in-situ consumption. View Full-Text
Keywords: diazonium salts; flow chemistry; meso reactor; processing; supported reagent diazonium salts; flow chemistry; meso reactor; processing; supported reagent

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Hu, T.; Baxendale, I.R.; Baumann, M. Exploring Flow Procedures for Diazonium Formation. Molecules 2016, 21, 918.

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