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Molecules 2016, 21(1), 107;

An Amidochlorin-Based Colorimetric Fluorescent Probe for Selective Cu2+ Detection

Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of Education, College of Chemistry & Chemical Engineering, Harbin Normal University, Harbin 150025, China
These authors contributed equally to this work.
Authors to whom correspondence should be addressed.
Academic Editors: Scott Reed and Marino Resendiz
Received: 5 December 2015 / Revised: 13 January 2016 / Accepted: 14 January 2016 / Published: 18 January 2016
(This article belongs to the Special Issue Photoactive Molecules)
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The design and synthesis of selective and sensitive chemosensors for the quantification of environmentally and biologically important ionic species has attracted widespread attention. Amidochlorin p6 (ACP); an effective colorimetric and fluorescent probe for copper ions (Cu2+) in aqueous solution derived from methyl pheophorbide-a (MPa) was designed and synthesized. A remarkable color change from pale yellow to blue was easily observed by the naked eye upon addition of Cu2+; and a fluorescence quenching was also determined. The research of fluorescent quenching of ACP-Cu2+ complexation showed the detection limit was 7.5 × 10−8 mol/L; which suggested that ACP can act as a high sensitive probe for Cu2+ and can be used to quantitatively detect low levels of Cu2+ in aqueous solution. In aqueous solution the probe exhibits excellent selectivity and sensitivity toward Cu2+ ions over other metal ions (M = Zn2+; Ni2+; Ba2+; Ag+; Co2+; Na+; K+; Mg2+; Cd2+; Pb2+; Mn2+; Fe3+; and Ca2+). The obvious change from pale yellow to blue upon the addition of Cu2+ could make it a suitable “naked eye” indicator for Cu2+. View Full-Text
Keywords: fluorescent probe; copper ions; chlorophyll fluorescent probe; copper ions; chlorophyll

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Li, W.; Zhu, G.; Li, J.; Wang, Z.; Jin, Y. An Amidochlorin-Based Colorimetric Fluorescent Probe for Selective Cu2+ Detection. Molecules 2016, 21, 107.

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