Next Article in Journal
Synthesis, Biological Activities, and Quantitative Structure–Activity Relationship (QSAR) Study of Novel Camptothecin Analogues
Previous Article in Journal
Biological Activity and Photostability of Biflorin Micellar Nanostructures
Open AccessReview

Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and Chemistry

Rome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy
*
Author to whom correspondence should be addressed.
R.R. dedicates this work to the memory of his friend Aldo Peparello, passed away prematurely. Without his support this study would not have been conceived.
Academic Editor: Derek J. McPhee
Molecules 2015, 20(5), 8605-8633; https://doi.org/10.3390/molecules20058605
Received: 12 April 2015 / Revised: 3 May 2015 / Accepted: 8 May 2015 / Published: 13 May 2015
(This article belongs to the Section Natural Products Chemistry)
Since herbal medicines play an important role in the treatment of a wide range of diseases, there is a growing need for their quality control and standardization. Mentha suaveolens Ehrh. (MS) is an aromatic herb with fruit and a spearmint flavor, used in the Mediterranean areas as a traditional medicine. It has an extensive range of biological activities, including cytotoxic, antimicrobial, antioxidant, anti-inflammatory, hypotensive and insecticidal properties, among others. This study aims to review the scientific findings and research reported to date on MS that prove many of the remarkable various biological actions, effects and some uses of this species as a source of bioactive natural compounds. On the other hand, piperitenone oxide (PO), the major chemical constituent of the carvone pathway MS essential oil, has been reported to exhibit numerous bioactivities in cells and animals. Thus, this integrated overview also surveys and interprets the present knowledge of chemistry and analysis of this oxygenated monoterpene, as well as its beneficial bioactivities. Areas for future research are suggested. View Full-Text
Keywords: Mentha suaveolens Ehrh.; essential oil; extracts; piperitenone oxide; biological activity Mentha suaveolens Ehrh.; essential oil; extracts; piperitenone oxide; biological activity
Show Figures

Graphical abstract

MDPI and ACS Style

Božović, M.; Pirolli, A.; Ragno, R. Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and Chemistry. Molecules 2015, 20, 8605-8633.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop