Cross-Coupling Synthesis of Methylallyl Alkenes: Scope Extension and Mechanistic Study
Abstract
:1. Introduction
2. Results and Discussion
2.1. Reaction Conditions Optimization
Entry | Alkenes | Side Product | Yield (%) 1,2 | |
---|---|---|---|---|
1 | 1 | 51 | ||
2 | 2 | 95 | ||
3 | 3/3′ | 52/38 | ||
4 | 4 | 55 | ||
5 | 5 | 77 | ||
6 | 6 | 78 | ||
7 | 7 | 80 | ||
8 | 8 | 57 | ||
9 | 9/9′ | 45/30 | ||
10 | 10/10′ | 41/42 | ||
11 | 11 | 77 | ||
12 | 12 | 50 | ||
13 | 13 | 46 |
Entry | Alkenes | Yield (%) 1 |
---|---|---|
14 | 61 2 | |
15 | 74 3 | |
16 | 97 3 | |
17 | 78 3 | |
18 | 97 3 | |
19 | 99 2 | |
20 | 92 3 | |
21 | 88 3 |
2.2. Mechanistic Study
3. Materials and Methods
3.1. General Information
3.2. Synthesis of Methylallyl Alkenes
3.3. Synthesis of 2,4,6-tri-p-Tolyl-1,3,5,2,4,6-trioxatriborinane
4. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Tabélé, C.; Curti, C.; Kabri, Y.; Primas, N.; Vanelle, P. Cross-Coupling Synthesis of Methylallyl Alkenes: Scope Extension and Mechanistic Study. Molecules 2015, 20, 22890-22899. https://doi.org/10.3390/molecules201219886
Tabélé C, Curti C, Kabri Y, Primas N, Vanelle P. Cross-Coupling Synthesis of Methylallyl Alkenes: Scope Extension and Mechanistic Study. Molecules. 2015; 20(12):22890-22899. https://doi.org/10.3390/molecules201219886
Chicago/Turabian StyleTabélé, Clémence, Christophe Curti, Youssef Kabri, Nicolas Primas, and Patrice Vanelle. 2015. "Cross-Coupling Synthesis of Methylallyl Alkenes: Scope Extension and Mechanistic Study" Molecules 20, no. 12: 22890-22899. https://doi.org/10.3390/molecules201219886