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Molecules 2014, 19(9), 13042-13060;

Alkaloids from the Tribe Bocconieae (Papaveraceae): A Chemical and Biological Review

Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China
These authors contributed equally to the work.
Authors to whom correspondence should be addressed.
Received: 14 May 2014 / Accepted: 20 August 2014 / Published: 25 August 2014
(This article belongs to the Special Issue Alkaloids: Novel Therapeutic Perspectives)
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The Bocconieae tribe, consisting of only the genera Macleaya and Bocconia, possesses significant economic and medicinal value and plays an important role in health management for people in developing countries. During the past decades, research on metabolites and relative pharmacology, including the isolation and identification of a variety of molecules, has shed light on the tribe. Among those molecules, isoquinoline alkaloids, and their antimicrobial, antifungal, and anti-inflammatory activities are especially noteworthy. This paper presents a comprehensive compilation of current research progress, with emphasis on the alkaloids and their distribution, phytochemical and pharmacological investigation, toxicity and side effects, related chemotaxonomy and future use prospects, and hopefully provides a valuable reference as an effort to promote further exploration and application of this tribe. View Full-Text
Keywords: Papaveraceae; Macleaya; Bocconia; alkaloids; bioactivity; review Papaveraceae; Macleaya; Bocconia; alkaloids; bioactivity; review

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Yu, X.; Gao, X.; Zhu, Z.; Cao, Y.; Zhang, Q.; Tu, P.; Chai, X. Alkaloids from the Tribe Bocconieae (Papaveraceae): A Chemical and Biological Review. Molecules 2014, 19, 13042-13060.

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