Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins
Abstract
:1. Introduction
2. Biological Studies with Crude Copaiba Oleoresins
Species | Biological activity evaluated | Ref. |
---|---|---|
C. cearensis Huber ex Ducke | Antimicrobial | [13] |
Anti-inflammatory | [14] | |
Antileishmanial | [15] | |
C. duckei Dwyer | antiproliferative | [16] |
Antimutagenic | [17] | |
Embriotoxicity | [18] | |
Anti-inflammatory | [19] | |
Analgesic | [19] | |
C. langsdorffii Desf. | Antimicrobial | [13,20,21,22,23] |
Attenuation of ischemia/reperfusion-induced intestinal | [24] | |
Gastroprotective effect on experimental gastric ulcer models in rats | [25] | |
C. langsdorffii Desf. | Ischemia-Reperfusion of Randomized Skin Flaps | [26] |
Antileishmanial | [15] | |
Wound Healing | [27,28,29] | |
Antioxidant | [30] | |
Insecticide | [31] | |
Anti-inflammatory | [32,33] | |
Antimutagenic | [34] | |
C. lucens Dwyer | Antimicrobial | [13] |
Antileishmanial | [15] | |
C. martii Hayne | Antimicrobial | [13] |
Antileishmanial | [15,35] | |
C. multijuga Hayne | Anti-inflammatory | [14,36,37,38] |
Antimicrobial | [13,39,40,41,42] | |
Antitumor | [43,44] | |
Antinociceptive | [36,45] | |
Antileishmanial | [15] | |
Healing | [46] | |
C. officinalis (Jacq.) L. | Antimicrobial | [13,22,23,47,48] |
Antischemic | [49] | |
Anti-inflammatory | [50] | |
Antileishmanial | [15] | |
Inhibition of human leukocyte elastase | [51] | |
Effect Antitumor (Walker 256 carcinoma) | [52] | |
C. paupera (Herzog) Dwyer | Antimicrobial | [13] |
Antileishmanial | [15,53] | |
C. reticulata Ducke | Antiinflammatory | [14] |
Antimicrobial | [13,54] | |
Inseticide | [55,56,57,58] | |
Antinociceptive | [45] | |
Teratogenicity and embriotoxicity | [59] | |
Toxicity | [60] | |
Antileishmanial | [15,61] | |
Wound Healing | [62,63] | |
Anxiolytic | [64] | |
C. sp. (commercial copaiba oleoresins) | Antimicrobial | [40] |
Anti-inflammatory | [65,66] | |
Skin perfusion | [67] | |
Insecticide | [68,69,70,71] |
3. Chemical Composition of Copaiba Oleoresins
3.1. Pharmacological Activities of the Main Sesquiterpenes from Copaiba Oleoresin
3.2. Pharmacological Activities of the Main Diterpenes from Copaiba Oleoresin
4. Conclusions
Acknowledgments
Conflict of Interest
References
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Leandro, L.M.; De Sousa Vargas, F.; Barbosa, P.C.S.; Neves, J.K.O.; Da Silva, J.A.; Da Veiga-Junior, V.F. Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins. Molecules 2012, 17, 3866-3889. https://doi.org/10.3390/molecules17043866
Leandro LM, De Sousa Vargas F, Barbosa PCS, Neves JKO, Da Silva JA, Da Veiga-Junior VF. Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins. Molecules. 2012; 17(4):3866-3889. https://doi.org/10.3390/molecules17043866
Chicago/Turabian StyleLeandro, Lidiam Maia, Fabiano De Sousa Vargas, Paula Cristina Souza Barbosa, Jamilly Kelly Oliveira Neves, José Alexsandro Da Silva, and Valdir Florêncio Da Veiga-Junior. 2012. "Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins" Molecules 17, no. 4: 3866-3889. https://doi.org/10.3390/molecules17043866
APA StyleLeandro, L. M., De Sousa Vargas, F., Barbosa, P. C. S., Neves, J. K. O., Da Silva, J. A., & Da Veiga-Junior, V. F. (2012). Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins. Molecules, 17(4), 3866-3889. https://doi.org/10.3390/molecules17043866