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Article

A New Iridoid Glycoside from the Roots of Dipsacus asper

by
De Ji
,
Chunfeng Zhang
,
Jingzhi Li
,
Haowei Yang
,
Jingyang Shen
and
Zhonglin Yang
*
State Key Laboratory of Natural Products and Functions, China Pharmaceutical University, Ministry of Education, 24 Tong Jia Xiang, Nanjing 210009, China
*
Author to whom correspondence should be addressed.
Molecules 2012, 17(2), 1419-1424; https://doi.org/10.3390/molecules17021419
Submission received: 13 January 2012 / Revised: 21 January 2012 / Accepted: 30 January 2012 / Published: 3 February 2012
(This article belongs to the Section Natural Products Chemistry)
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Abstract

A new iridoid glycoside, named loganic acid ethyl ester (1), together with five known compounds: chlorogenic acid (2), caffeic acid (3), loganin (4), cantleyoside (5) and syringaresinol-4′,4′′-O-bis-β-D-glucoside (6) were isolated from the roots of Dipsacus asper. The structure of compound 1 was elucidated on the basis of detailed spectroscopic analyses. Lignan is isolated from Dipsacaceae species for the first time. Compounds 1, 4 and 5 had moderate neuroprotective effects against the Aβ25–35 induced cell death in PC12 cells.
Keywords: Dipsacus asper; iridoid glycoside; loganic acid ethyl ester; neuroprotective effect; Dipsaceae Dipsacus asper; iridoid glycoside; loganic acid ethyl ester; neuroprotective effect; Dipsaceae
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MDPI and ACS Style

Ji, D.; Zhang, C.; Li, J.; Yang, H.; Shen, J.; Yang, Z. A New Iridoid Glycoside from the Roots of Dipsacus asper. Molecules 2012, 17, 1419-1424. https://doi.org/10.3390/molecules17021419

AMA Style

Ji D, Zhang C, Li J, Yang H, Shen J, Yang Z. A New Iridoid Glycoside from the Roots of Dipsacus asper. Molecules. 2012; 17(2):1419-1424. https://doi.org/10.3390/molecules17021419

Chicago/Turabian Style

Ji, De, Chunfeng Zhang, Jingzhi Li, Haowei Yang, Jingyang Shen, and Zhonglin Yang. 2012. "A New Iridoid Glycoside from the Roots of Dipsacus asper" Molecules 17, no. 2: 1419-1424. https://doi.org/10.3390/molecules17021419

APA Style

Ji, D., Zhang, C., Li, J., Yang, H., Shen, J., & Yang, Z. (2012). A New Iridoid Glycoside from the Roots of Dipsacus asper. Molecules, 17(2), 1419-1424. https://doi.org/10.3390/molecules17021419

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