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Molecules 2012, 17(1), 295-302;

A New Triterpenoid Saponin from Abrus precatorius Linn

Key Laboratory of Marine Bio-Resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
Graduate University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China
Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Second Military Medical University, Shanghai 200433, China
Author to whom correspondence should be addressed.
Received: 30 November 2011 / Revised: 20 December 2011 / Accepted: 23 December 2011 / Published: 30 December 2011
(This article belongs to the Section Natural Products Chemistry)
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A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems of Abrus precatorius. Their structures were elucidated on the basis of physical and NMR analysis, respectively. Compounds 5 and 6 showed moderate cytotoxicity against MCF-7, SW1990, Hela, and Du-145 cell lines. Compounds 1, 2 and 4 were isolated from this plant for the first time. View Full-Text
Keywords: Abrus precarorius Linn; triterpenoid; saponin; cytotoxicity Abrus precarorius Linn; triterpenoid; saponin; cytotoxicity

Figure 1

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Xiao, Z.-H.; Wang, F.-Z.; Sun, A.-J.; Li, C.-R.; Huang, C.-G.; Zhang, S. A New Triterpenoid Saponin from Abrus precatorius Linn. Molecules 2012, 17, 295-302.

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