Antiradical, Chelating and Antioxidant Activities of Hydroxamic Acids and Hydroxyureas
Abstract
:1. Introduction
2. Results and Discussion
2.1. DPPH Radical Scavenging Activity
Compound | Log P | ANT (%) a,b | AA-60 (%) a,c |
---|---|---|---|
1 | 3.12 | 62.45 ± 5.55 * | 63.46 ± 3.01 * |
2 | 2.30 | 64.47 ± 5.55 * | 65.72 ± 3.06 * |
3 | 3.23 | 60.67 ± 5.43 * | 63.15 ± 3.37 * |
4 | 2.46 | 60.66 ± 1.38 * | 62.80 ± 0.89 * |
5 | 3.41 | 67.33 ± 4.71 * | 69.93 ± 2.84 * |
6 | 2.02 | 72.73 ± 2.45 * | 73.76 ± 1.14 |
7 | 3.79 | 89.13 ± 1.89 † | 88.55 ± 0.92 |
8 | 3.34 | 88.61 ± 1.74 † | 88.03 ± 1.15 |
9 | 3.82 | 94.39 ± 1.03 † | 94.22 ± 1.19 |
10 | 4.25 | 89.86 ± 0.97 † | 89.54 ± 1.80 † |
11 | 1.53 | 54.96 ± 4.67 * | 57.43 ± 2.53 * |
BHA | n.c. | 79.59 ± 2.06 | 80.55 ± 1.43 |
2.2. Chelating Activity
2.3. β-Carotene Linoleic Acid Assay
3. Experimental
3.1. General
3.2. Chemicals
3.3. Antiradical Activity
3.4. Fe2+ Chelating Activity
3.5. β-Carotene-linoleic Acid Assay
3.6. Statistical and Log P Analysis
4. Conclusions
Acknowledgments
Conflict of Interest
References and Notes
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Končić, M.Z.; Barbarić, M.; Perković, I.; Zorc, B. Antiradical, Chelating and Antioxidant Activities of Hydroxamic Acids and Hydroxyureas. Molecules 2011, 16, 6232-6242. https://doi.org/10.3390/molecules16086232
Končić MZ, Barbarić M, Perković I, Zorc B. Antiradical, Chelating and Antioxidant Activities of Hydroxamic Acids and Hydroxyureas. Molecules. 2011; 16(8):6232-6242. https://doi.org/10.3390/molecules16086232
Chicago/Turabian StyleKončić, Marijana Zovko, Monika Barbarić, Ivana Perković, and Branka Zorc. 2011. "Antiradical, Chelating and Antioxidant Activities of Hydroxamic Acids and Hydroxyureas" Molecules 16, no. 8: 6232-6242. https://doi.org/10.3390/molecules16086232