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Open AccessArticle

Ultrasonication-Assisted Solvent Extraction of Quercetin Glycosides from ‘Idared’ Apple Peels

Tree Fruit Bio-product Research Program, Department of Environmental Sciences, Nova Scotia Agricultural College, P.O. Box 550, Truro, Nova Scotia, B2N 5E3, Canada
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Molecules 2011, 16(12), 9783-9791; https://doi.org/10.3390/molecules16129783
Received: 14 November 2011 / Revised: 22 November 2011 / Accepted: 22 November 2011 / Published: 25 November 2011
Quercetin and quercetin glycosides are physiologically active flavonol molecules that have been attributed numerous health benefits. Recovery of such molecules from plant matrices depends on a variety of factors including polarity of the extraction solvent. Among the solvents of a wide range of dielectric constants, methanol recovered the most quercetin and its glycosides from dehydrated ‘Idared’ apple peels. When ultra-sonication was employed to facilitate the extraction, exposure of 15 min of ultrasound wavelengths of dehydrated apple peel powder in 80% to 100% (v/v) methanol in 1:50 (w:v) solid to solvent ratio provided the optimum extraction conditions for quercetin and its glycosides. Acidification of extraction solvent with 0.1% (v/v) or higher concentrations of HCl led to hydrolysis of naturally occurring quercetin glycosides into the aglycone as an extraction artifact. View Full-Text
Keywords: flavonols; extraction; ultrasonication; quercetin; quercetin glycoside; acidification; apple flavonols; extraction; ultrasonication; quercetin; quercetin glycoside; acidification; apple
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Vasantha Rupasinghe, H.P.; Kathirvel, P.; Huber, G.M. Ultrasonication-Assisted Solvent Extraction of Quercetin Glycosides from ‘Idared’ Apple Peels. Molecules 2011, 16, 9783-9791.

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