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Molecules 2010, 15(10), 7227-7234;

Efficient Microwave-Assisted Synthesis of 5-Deazaflavine Derivatives

Grupo de Investigación en Compuestos Heterocíclicos, Programa de Química, Facultad de Ciencias Básicas, Universidad del Atlántico, A.A.1890 Barranquilla, Colombia
Grupo de Investigación de Compuestos Heterocíclicos, Departamento de Química, Universidad del Valle, A. A. 25360 Cali, Colombia
Departamento de Química Inorgánica y Orgánica, Universidad de Jaén, 23071 Jaén, Spain
Authors to whom correspondence should be addressed.
Received: 16 September 2010 / Revised: 30 September 2010 / Accepted: 3 October 2010 / Published: 20 October 2010
(This article belongs to the Section Organic Chemistry)
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A series of pyrimido[4,5-b]quinolines (5-deazaflavines), were synthesized by microwave assisted intramolecular cyclization. The N4-substituted-2,4-diamino-6-chloro-pyrimidine-5-carbaldehydes, were prepared by selective monoamination of 2-amino-4,6-dichloropyrimidine-5-carbaldehyde with aliphatic and aromatic amines. View Full-Text
Keywords: pyrimidoquinolines; cyclocondensation; microwave; deazaflavines pyrimidoquinolines; cyclocondensation; microwave; deazaflavines

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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Trilleras, J.; López, L.G.; Pacheco, D.J.; Quiroga, J.; Nogueras, M.; Torre, J.M.; Cobo, J. Efficient Microwave-Assisted Synthesis of 5-Deazaflavine Derivatives. Molecules 2010, 15, 7227-7234.

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