Next Article in Journal
X-ray and Hydrogen-bonding Properties of 1-((1H-benzotriazol-1-yl)methyl)naphthalen-2-ol
Next Article in Special Issue
(+)-N-(2-Hydroxypropyl)lindcarpine: A New Cytotoxic Aporphine Isolated from Actinodaphne pruinosa Nees
Previous Article in Journal
Current Status of Older and New Purine Nucleoside Analogues in the Treatment of Lymphoproliferative Diseases
Previous Article in Special Issue
Total Syntheses of Telisatin A, Telisatin B and Lettowianthine
Open AccessArticle

Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis

1
Centre for Natural Products and Drug Discovery, Block D, Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
2
Institut de Chimie des Substances Naturelles, Centre Nationale de la Recherche Scientifique, UPR2301, 91198, Gif-sur-Yvette, Cedex, France
3
Department of Chemical Sciences, Faculty of Science and Technology, Universiti Malaysia Terengganu, 21030 Kuala Terengganu, Terengganu, Malaysia
*
Author to whom correspondence should be addressed.
Molecules 2009, 14(3), 1227-1233; https://doi.org/10.3390/molecules14031227
Received: 23 December 2008 / Revised: 13 February 2009 / Accepted: 18 February 2009 / Published: 23 March 2009
(This article belongs to the Special Issue Aporphines and Oxoaporphines)
The stem bark of Phoebe grandis afforded one new oxoproaporphine; (–)-grandine A (1), along with six known isoquinoline alkaloids: (–)-8,9-dihydrolinearisine (2), boldine, norboldine, lauformine, scortechiniine A and scortechiniine B. In addition to that of the new compound, complete 1H- and 13C-NMR data of the tetrahydroproaporphine (–)-8,9-dihydrolinearisine (2) is also reported. The alkaloids’ structures were elucidated primarily by means of high field 1D- and 2D-NMR and HRMS spectral data. View Full-Text
Keywords: Oxoproaporphine; NMR; Phoebe grandis; Aporphine; Dihydrolinearisine Oxoproaporphine; NMR; Phoebe grandis; Aporphine; Dihydrolinearisine
Show Figures

Graphical abstract

MDPI and ACS Style

Mukhtar, M.R.; Aziz, A.N.; Thomas, N.F.; Hadi, A.H.A.; Litaudon, M.; Awang, K. Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis. Molecules 2009, 14, 1227-1233.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop