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Keywords = Oxoproaporphine

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Article
Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
by Mat Ropi Mukhtar, Ahmad Nazif Aziz, Noel F. Thomas, A. Hamid A. Hadi, Marc Litaudon and Khalijah Awang
Molecules 2009, 14(3), 1227-1233; https://doi.org/10.3390/molecules14031227 - 23 Mar 2009
Cited by 14 | Viewed by 14987
Abstract
The stem bark of Phoebe grandis afforded one new oxoproaporphine; (–)-grandine A (1), along with six known isoquinoline alkaloids: (–)-8,9-dihydrolinearisine (2), boldine, norboldine, lauformine, scortechiniine A and scortechiniine B. In addition to that of the new compound, complete 1H- and 13C-NMR [...] Read more.
The stem bark of Phoebe grandis afforded one new oxoproaporphine; (–)-grandine A (1), along with six known isoquinoline alkaloids: (–)-8,9-dihydrolinearisine (2), boldine, norboldine, lauformine, scortechiniine A and scortechiniine B. In addition to that of the new compound, complete 1H- and 13C-NMR data of the tetrahydroproaporphine (–)-8,9-dihydrolinearisine (2) is also reported. The alkaloids’ structures were elucidated primarily by means of high field 1D- and 2D-NMR and HRMS spectral data. Full article
(This article belongs to the Special Issue Aporphines and Oxoaporphines)
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