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Phytochemical Contents and Antioxidant Capacities of Two Aloe greatheadii var. davyana Extracts

School for Physiology, Nutrition and Consumer’s Science, Private Bag X6001, Box 594, Potchefstroom, 2531, South Africa
School for Physical and Chemical Sciences, North-West University, Private Bag X6001, Box 269, Potchefstroom, 2531, South Africa
Author to whom correspondence should be addressed.
Molecules 2008, 13(9), 2169-2180;
Received: 10 June 2008 / Revised: 22 August 2008 / Accepted: 23 August 2008 / Published: 12 September 2008
(This article belongs to the Special Issue Phenolics and Polyphenolics)
Aloe greatheadii var. davyana (Asphodelaceae) is used among rural South African communities to treat arthritis, skin cancer, burns, eczema, psoriasis, digestive problems, high blood pressure and diabetes, despite very little supporting scientific evidence. Due to increased interest by both the scientific community and industry regarding the medicinal uses of this plant species, we identified, quantified and compared the phytochemical contents and antioxidant capacities of two extracts of A. greatheadii; a leaf gel extract (LGE) and a 95 % aqueous ethanol leaf gel extract (ELGE), using various modified extraction procedures, GC-MS and spectrophotometry. Apart from extensively characterizing this medicinal plant with regards to its organic acid, polyphenols/phenolic acid, alcohol, aldehyde, ketone, alkane, pyrimidine, indole, alkaloid, phytosterol, fatty acid and dicarboxylic acid contents and antioxidant capacities, we describe a modified extraction procedure for the purpose of general phytochemical characterization, and compare this to a 95 % aqueous ethanol extraction technique. From the results it is clear that A. greatheadii contains a variety of compounds with confirmed antioxidant capacity and other putative health benefits (such as blood glucose, cholesterol and cortisol lowering properties) relating to the prevention or treatment of diabetes, cardiovascular disease, cancer and hypertension. The results also indicate that separate ethyl acetate/diethyl ether and hexane extractions of the LGE, better serve for general phytochemical characterization purposes, and 95 % aqueous ethanol extraction for concentrating selective groups of health related compounds, hence justifying its use for biological in vivo efficacy studies. View Full-Text
Keywords: Phytochemical content; antioxidant capacity; polyphenols; phytosterols Phytochemical content; antioxidant capacity; polyphenols; phytosterols
MDPI and ACS Style

Botes, L.; Van der Westhuizen, F.H.; Loots, D.T. Phytochemical Contents and Antioxidant Capacities of Two Aloe greatheadii var. davyana Extracts. Molecules 2008, 13, 2169-2180.

AMA Style

Botes L, Van der Westhuizen FH, Loots DT. Phytochemical Contents and Antioxidant Capacities of Two Aloe greatheadii var. davyana Extracts. Molecules. 2008; 13(9):2169-2180.

Chicago/Turabian Style

Botes, Lisa, Francois H. Van der Westhuizen, and Du T. Loots. 2008. "Phytochemical Contents and Antioxidant Capacities of Two Aloe greatheadii var. davyana Extracts" Molecules 13, no. 9: 2169-2180.

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