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Article

Phenolic Compounds and Antimicrobial Activity of Olive (Olea europaea L. Cv. Cobrançosa) Leaves

1
CIMO / Escola Superior Agrária, Instituto Politécnico de Bragança, Campus Sta Apolónia, Apt. 1172, 5301-855 Bragança, Portugal
2
REQUIMTE / Serviço de Farmacognosia, Faculdade de Farmácia da Universidade do Porto, Rua Aníbal Cunha, 164, 4050-047 Porto, Portugal
*
Author to whom correspondence should be addressed.
Molecules 2007, 12(5), 1153-1162; https://doi.org/10.3390/12051153
Received: 23 February 2007 / Revised: 24 May 2007 / Accepted: 24 May 2007 / Published: 26 May 2007
(This article belongs to the Special Issue Phenolics and Polyphenolics)
We report the determination of phenolic compounds in olive leaves by reversed-phase HPLC/DAD, and the evaluation of their in vitro activity against several microorganisms that may be causal agents of human intestinal and respiratory tract infections, namely Gram positive (Bacillus cereus, B. subtilis and Staphylococcus aureus), Gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae) and fungi (Candida albicans and Cryptococcus neoformans). Seven phenolic compounds were identified and quantified: caffeic acid, verbascoside, oleuropein, luteolin 7-O-glucoside, rutin, apigenin 7-O-glucoside and luteolin 4’-O-glucoside. At low concentrations olive leafs extracts showed an unusual combined antibacterial and antifungal action, which suggest their great potential as nutraceuticals, particulalry as a source of phenolic compounds. View Full-Text
Keywords: Olive leaves; Phenolic compounds; Antibacterial activity; Antifungal activity Olive leaves; Phenolic compounds; Antibacterial activity; Antifungal activity
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MDPI and ACS Style

Pereira, A.P.; Ferreira, I.C.; Marcelino, F.; Valentão, P.; Andrade, P.B.; Seabra, R.; Estevinho, L.; Bento, A.; Pereira, J.A. Phenolic Compounds and Antimicrobial Activity of Olive (Olea europaea L. Cv. Cobrançosa) Leaves. Molecules 2007, 12, 1153-1162. https://doi.org/10.3390/12051153

AMA Style

Pereira AP, Ferreira IC, Marcelino F, Valentão P, Andrade PB, Seabra R, Estevinho L, Bento A, Pereira JA. Phenolic Compounds and Antimicrobial Activity of Olive (Olea europaea L. Cv. Cobrançosa) Leaves. Molecules. 2007; 12(5):1153-1162. https://doi.org/10.3390/12051153

Chicago/Turabian Style

Pereira, Ana P., Isabel C. Ferreira, Filipa Marcelino, Patricia Valentão, Paula B. Andrade, Rosa Seabra, Leticia Estevinho, Albino Bento, and José A. Pereira 2007. "Phenolic Compounds and Antimicrobial Activity of Olive (Olea europaea L. Cv. Cobrançosa) Leaves" Molecules 12, no. 5: 1153-1162. https://doi.org/10.3390/12051153

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