Special Issue "Utilization of Electrochemical Sensors and Biosensors in Biochemistry and Molecular Biology"

Guest Editor
Dr. René Kizek
Laboratory of Molecular Biochemistry and Bioelectrochemistry, Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University of Agriculture and Forestry, Zemedelska 1, CZ-613 00 Brno, Czech Republic
Website: https://is.mendelu.cz/lide/clovek.pl?id=12948;zalozka=5;lang=en
E-Mail:
Interests: electrochemical detection in biology; bioelectrochemistry; sensors; biosensors; peptides; proteins; nucleic acids

Biochemical and molecular-biological techniques still booms at all branches of biological research. Since successfully sequencing of human genome, rapid analysis of nucleic acids by various techniques has been developing intensively. The attention is mostly paid to recognizing of pathological sequence, which is related to diseases origin. Other field of research associated with nucleic acids analysis bases on studying and determining of changes of mRNA level as marker of various gene activity. “Switching of genes” is very common during development of all living beings, but the wrong timing of such switching can lead to many disorders and diseases including cancer. As it has been shown, count of human functional genes is very low, under 20 thousands (according to the last estimation), and thus can not be associated only with an organism development. Based on the mentioned facts, proteins are other group of biologically active compounds associated with the organism development. Research devoted to study of proteins called “proteomic research” is at very beginning.
Investigation the mentioned biological pathways can be done using battery techniques and methods. Very interesting and promising results bring techniques using various sensors and biosensors coupled with different types of detectors

This issue will include the following topics:

1. suggestion and construction of sensors and biosensors for molecular and biochemical applications;
2. new materials to construct of sensors (nanotechnology);
3. advantages and disadvantages of various types of detection of biologically important compounds;
4. sensors and biosensors for analysis of DNA and RNA;
5. sensors and biosensors for analysis of aminoacids, peptides and proteins;
6. chips and their utilizing for detection of DNA, RNA and proteins;
7. practical aspects of utilizing of sensors and biosensors in biology: estimation of specific sequence of animals, plants; monitoring of biomarkers; human and veterinary medicine (diagnostic of diseases).

• electrochemical sensors
• DNA sensors
• detection of proteins and DNA
• molecular biology
• cancer
• human disease
• sensor arrays
• DNA and RNA chips
• protein chips