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Sensors 2007, 7(12), 3299-3311; doi:10.3390/s7123299
Article

Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection

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Received: 12 November 2007; Accepted: 12 December 2007 / Published: 14 December 2007
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Abstract: Specially shaped gold nanoparticles have intrigued considerable attention becausethey usually possess high-sensitivity surface-enhanced Raman scattering (SERS) and thusresult in large advantages in trace biodetermination. In this article, starch-capped goldnanoparticles with hexagon and boot shapes were prepared through using a nontoxic andbiologically benign aqueous-phase synthetic route. Shape effects of gold nanoparticles onSERS properties were mainly investigated, and found that different-shaped goldnanoparticles possess different SERS properties. Especially, the boot-shaped nanoparticlescould induce more 100-fold SERS enhancements in sensitivity as compared with those fromgold nanospheres. The extremely strong SERS properties of gold nanoboots have beensuccessfully applied to the detection of avidin. The unique nanoboots with high-sensitivitySERS properties are also expected to find use in many other fields such as biolabel,bioassay, biodiagnosis, and even clinical diagnosis and therapy.
Keywords: Gold nanoparticle; Special shape; Surface-enhanced Raman scattering; Biodetection Gold nanoparticle; Special shape; Surface-enhanced Raman scattering; Biodetection
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Hu, J.; Wang, Z.; Li, J. Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection. Sensors 2007, 7, 3299-3311.

AMA Style

Hu J, Wang Z, Li J. Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection. Sensors. 2007; 7(12):3299-3311.

Chicago/Turabian Style

Hu, Jianqiang; Wang, Zhouping; Li, Jinghong. 2007. "Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection." Sensors 7, no. 12: 3299-3311.



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