Sensors 2007, 7(12), 3299-3311; doi:10.3390/s7123299
Article

Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection

Department of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing 100084, China
* Author to whom correspondence should be addressed.
Received: 12 November 2007; Accepted: 12 December 2007 / Published: 14 December 2007
PDF Full-text Download PDF Full-Text [1409 KB, uploaded 16 September 2008 11:01 CEST]
Abstract: Specially shaped gold nanoparticles have intrigued considerable attention becausethey usually possess high-sensitivity surface-enhanced Raman scattering (SERS) and thusresult in large advantages in trace biodetermination. In this article, starch-capped goldnanoparticles with hexagon and boot shapes were prepared through using a nontoxic andbiologically benign aqueous-phase synthetic route. Shape effects of gold nanoparticles onSERS properties were mainly investigated, and found that different-shaped goldnanoparticles possess different SERS properties. Especially, the boot-shaped nanoparticlescould induce more 100-fold SERS enhancements in sensitivity as compared with those fromgold nanospheres. The extremely strong SERS properties of gold nanoboots have beensuccessfully applied to the detection of avidin. The unique nanoboots with high-sensitivitySERS properties are also expected to find use in many other fields such as biolabel,bioassay, biodiagnosis, and even clinical diagnosis and therapy.
Keywords: Gold nanoparticle; Special shape; Surface-enhanced Raman scattering; Biodetection

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Hu, J.; Wang, Z.; Li, J. Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection. Sensors 2007, 7, 3299-3311.

AMA Style

Hu J, Wang Z, Li J. Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection. Sensors. 2007; 7(12):3299-3311.

Chicago/Turabian Style

Hu, Jianqiang; Wang, Zhouping; Li, Jinghong. 2007. "Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection." Sensors 7, no. 12: 3299-3311.

Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert