Special Issue "Mycotoxins: Mechanisms of Toxicological Activity - Treatment and Prevention"

Quicklinks

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology".

Deadline for manuscript submissions: closed (31 October 2008)

Special Issue Editor

Guest Editor
Dr. Vesna Jacevic
National Poison Control Centre, Military Medical Academy, Crnotravska 17, 11002 Belgrade, Republic of Serbia
E-Mail: petmedic@net.yu

Special Issue Information

Dear Colleagues,

By the mid-twentieth century, it was proved that mycotoxins were cause of sporadic, spontaneous and severe intoxications in humans and animals through the world. The toxic effects of mycotoxins on human health are complex and little understood. Furthermore, in warm, humid developing countries, regular mycotoxin presence in the diet affects human populations and domesticated animals, causing morbidity and premature deaths. Toxicological characteristics of mycotoxins (significant persistence in the environment, cheap manufacture and difficult detection) were studied extensively worldwide throughout the 20th century, but the exact mechanisms of their actions, as well as specific antidotes, are not known so far. In this special issue, original reaserch findings and review articles with regards to the mechanisms, treatment and prevention of mycotoxins are considered for publication.

Dr. Vesna Jacevic
Guest Editor

Leading Papers and Reviews

  • Bennett, J.W.; Klich, M. Mycotoxins. Clin. Microbiol. Rev. 2003, 16, 497-516.
  • Chivasa, S.; Ndimba, B.K.; Simon, W.J.; Lindsey, K.; Slabas, A.R. Extracellular ATP functions as an endogenous external metabolite regulating plant cell viability. Plant Cell 2005, 17, 3019-3034.
  • Chu, F.S. Trichothecene mycotoxicoses. Encyclop. Hum. Biol. 1997, 8, 511-522.
  • Creppy, E.E. Human ochratoxicosis. J. Toxicol. Toxin. Rev. 1999, 18, 277-293.
  • Etzel, R.A. Mycotoxins. J. Am. Med. Assoc. 2002, 287, 425-427.
  • Hedayati, M.T.; Pasqualotto, A.C.; Warn, P.A.; Bowyer, P.; Denning, D.W. Aspergillus flavus: human pathogen, allergen and mycotoxin producer. Microbiol. 2007, 153, 1677-1692.
  • Josephs, R.D.; Derbyshire, M.; Stroka, J.; Emons, H.; Anklam, E. Trichothecenes: reference materials and method validation. Toxicol. Lett. 2004, 153, 123-132.
  • Kemppainen, B.W.; Riley, R.T.; Pace, J.G. Skin absorption as a route of exposure for aflatoxin and trichothecenes. J. Toxicol. Toxin. Rev. 1988-89, 7, 95-120.
  • Krska, R.; Baumgartner, S.; Josephs, R. Review: The state-of-art in the analysis of type-A and -B trichothecene mycotoxins in cereals. J. Anal. Chem. 2001, 71, 285-299.
  • Larsen, J.C.; Hunt, J.; Perrin, I.; Ruckenbauer, P. Workshop on trichothecenes with a focus on DON: summary report. Toxicol. Lett. 2004, 153, 1-22.
  • Moon, Y.; Pestka, J.J. Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases. Toxicol. Sci. 2002, 69, 373-382.
  • Parent-Massin. D.; Parchment. R. Hematotoxicity of mycotoxins. Rev. Med. Vet. 1998, 149, 591-598.
  • Parent-Massin, D. Haematotoxicity of trichothecenes. Toxicol. Lett. 2004, 153, 75-81.
  • Pestka, J.J.; Zhou, H.R. Interleukin-6-deficient mice refractory to IgA dysregulation but not anorexia induction by vomitoxin ingestion. Food Chem. Toxicol. 2000, 38, 565-575.
  • Pestka, J.J.; Zhou, H.R.; Moon, Y.; Chung, Y.J. Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox. Toxicol. Lett. 2004, 153, 61-73.
  • Schlatter, J. Toxicity data relevant for hazard characterization. Toxicol. Lett. 2004, 153, 83-89.
  • Speijers, G.J.A.; Speijers, M.H.M. Combined toxic effects of mycotoxins. Toxicol. Lett. 2004, 153, 918.
  • Sudakin, D.L. Trichothecenes in the environment: relevance to human health. Toxicol. Lett. 2003, 143, 97-107.
  • Pestka, J.J.; Smolinski, A.T. Deoxynivalenol: Toxicology and potential effects on humans. J. Toxicol. Environ. Health B Crit. Rev. 2005, 8 39-69.

Keywords

  • acute intoxications
  • aflatoxin
  • alimentary disorders
  • analytic methods
  • antagonism of mycotoxins
  • antidotes
  • apoptosis
  • carcinogenicity of mycotoxins
  • chemical stability
  • chronic intoxications
  • dermal effects
  • cardiotoxicity
  • diagnosis
  • DNA alterations
  • mitohondrial alteration
  • food safety
  • gene expression
  • haematoxicity
  • Hazard analysis
  • hepatotoxicity
  • humans
  • immunotoxicity
  • in vitro and in vivo tests
  • laboratory animals
  • domestic animals
  • macrocyclic trichothecenes
  • medical treatment
  • necrosis
  • nephrotoxicity
  • ochratoxin
  • penicillium
  • prevention
  • synergism of mycotoxins
  • combination toxicology
  • zearalenone

Published Papers (34 papers)

Download All Papers
Sort by:
Display options:
Select articles Export citation of selected articles as:
Select/unselect all
Displaying article 1-34
p. 1465-1475
by , ,  and
Int. J. Mol. Sci. 2009, 10(4), 1465-1475; doi:10.3390/ijms10041465
Received: 4 February 2009; in revised form: 13 March 2009 / Accepted: 27 March 2009 / Published: 1 April 2009
Show/Hide Abstract | Cited by 11 | PDF Full-text (85 KB) | HTML Full-text | XML Full-text
p. 1138-1160
by , , ,  and
Int. J. Mol. Sci. 2009, 10(3), 1138-1160; doi:10.3390/ijms10031138
Received: 3 January 2009; in revised form: 28 February 2009 / Accepted: 9 March 2009 / Published: 12 March 2009
Show/Hide Abstract | Cited by 6 | PDF Full-text (644 KB) | HTML Full-text | XML Full-text
p. 395-406
by , , ,  and
Int. J. Mol. Sci. 2009, 10(2), 395-406; doi:10.3390/ijms10020395
Received: 21 November 2008; in revised form: 5 January 2009 / Accepted: 6 January 2009 / Published: 1 February 2009
Show/Hide Abstract | Cited by 3 | PDF Full-text (363 KB) | HTML Full-text | XML Full-text
p. 147-173
by  and
Int. J. Mol. Sci. 2009, 10(1), 147-173; doi:10.3390/ijms10010147
Received: 7 November 2008; in revised form: 16 December 2008 / Accepted: 5 January 2009 / Published: 6 January 2009
Show/Hide Abstract | Cited by 56 | PDF Full-text (128 KB) | HTML Full-text | XML Full-text
p. 174-183
by , ,  and
Int. J. Mol. Sci. 2009, 10(1), 174-183; doi:10.3390/ijms10010174
Received: 5 November 2008; in revised form: 10 December 2008 / Accepted: 29 December 2008 / Published: 6 January 2009
Show/Hide Abstract | Cited by 14 | PDF Full-text (132 KB) | HTML Full-text | XML Full-text
p. 62-115
by  and
Int. J. Mol. Sci. 2009, 10(1), 62-115; doi:10.3390/ijms10010062
Received: 29 October 2008; in revised form: 24 November 2008 / Accepted: 1 January 2009 / Published: 2 January 2009
Show/Hide Abstract | Cited by 38 | PDF Full-text (350 KB) | HTML Full-text | XML Full-text
p. 1-17
by , , , , ,  and
Int. J. Mol. Sci. 2009, 10(1), 1-17; doi:10.3390/ijms10010001
Received: 6 November 2008; in revised form: 22 December 2008 / Accepted: 24 December 2008 / Published: 27 December 2008
Show/Hide Abstract | Cited by 10 | PDF Full-text (195 KB) | HTML Full-text | XML Full-text
p. 37-49
by  and
Int. J. Mol. Sci. 2009, 10(1), 37-49; doi:10.3390/ijms10010037
Received: 5 November 2008; in revised form: 15 December 2008 / Accepted: 18 December 2008 / Published: 27 December 2008
Show/Hide Abstract | Cited by 1 | PDF Full-text (333 KB) | HTML Full-text | XML Full-text
p. 2614-2621
by , , ,  and
Int. J. Mol. Sci. 2008, 9(12), 2614-2621; doi:10.3390/ijms9122614
Received: 27 October 2008; in revised form: 5 December 2008 / Accepted: 10 December 2008 / Published: 12 December 2008
Show/Hide Abstract | Cited by 13 | PDF Full-text (183 KB) | HTML Full-text | XML Full-text
p. 2570-2584
by  and
Int. J. Mol. Sci. 2008, 9(12), 2570-2584; doi:10.3390/ijms9122570
Received: 3 November 2008; in revised form: 4 December 2008 / Accepted: 8 December 2008 / Published: 11 December 2008
Show/Hide Abstract | Cited by 33 | PDF Full-text (169 KB) | HTML Full-text | XML Full-text
p. 2585-2600
by ,  and
Int. J. Mol. Sci. 2008, 9(12), 2585-2600; doi:10.3390/ijms9122585
Received: 23 October 2008; in revised form: 8 December 2008 / Accepted: 10 December 2008 / Published: 11 December 2008
Show/Hide Abstract | Cited by 5 | PDF Full-text (184 KB) | HTML Full-text | XML Full-text
p. 2543-2558
by
Int. J. Mol. Sci. 2008, 9(12), 2543-2558; doi:10.3390/ijms9122543
Received: 7 November 2008; in revised form: 8 December 2008 / Accepted: 10 December 2008 / Published: 10 December 2008
Show/Hide Abstract | Cited by 9 | PDF Full-text (209 KB) | HTML Full-text | XML Full-text
p. 2505-2514
by , ,  and
Int. J. Mol. Sci. 2008, 9(12), 2505-2514; doi:10.3390/ijms9122505
Received: 16 October 2008; in revised form: 20 November 2008 / Accepted: 3 December 2008 / Published: 8 December 2008
Show/Hide Abstract | Cited by 1 | PDF Full-text (116 KB) | HTML Full-text | XML Full-text
p. 2474-2494
by , ,  and
Int. J. Mol. Sci. 2008, 9(12), 2474-2494; doi:10.3390/ijms9122474
Received: 29 September 2008; in revised form: 20 November 2008 / Accepted: 3 December 2008 / Published: 5 December 2008
Show/Hide Abstract | Cited by 10 | PDF Full-text (978 KB) | HTML Full-text | XML Full-text
abstract graphic
p. 2495-2504
by , , , , ,  and
Int. J. Mol. Sci. 2008, 9(12), 2495-2504; doi:10.3390/ijms9122495
Received: 6 November 2008; in revised form: 20 November 2008 / Accepted: 3 December 2008 / Published: 5 December 2008
Show/Hide Abstract | Cited by 17 | PDF Full-text (117 KB) | HTML Full-text | XML Full-text
p. 2366-2375
by , ,  and
Int. J. Mol. Sci. 2008, 9(12), 2366-2375; doi:10.3390/ijms9122366
Received: 14 June 2008; in revised form: 13 November 2008 / Accepted: 25 November 2008 / Published: 27 November 2008
Show/Hide Abstract | Cited by 12 | PDF Full-text (612 KB) | HTML Full-text | XML Full-text
p. 2357-2365
by , ,  and
Int. J. Mol. Sci. 2008, 9(12), 2357-2365; doi:10.3390/ijms9122357
Received: 17 September 2008; in revised form: 31 October 2008 / Accepted: 25 November 2008 / Published: 26 November 2008
Show/Hide Abstract | Cited by 5 | PDF Full-text (163 KB) | HTML Full-text | XML Full-text
p. 2306-2321
by  and
Int. J. Mol. Sci. 2008, 9(11), 2306-2321; doi:10.3390/ijms9112306
Received: 28 August 2008; in revised form: 19 November 2008 / Accepted: 24 November 2008 / Published: 25 November 2008
Show/Hide Abstract | Cited by 19 | PDF Full-text (362 KB) | HTML Full-text | XML Full-text
p. 2205-2216
by ,  and
Int. J. Mol. Sci. 2008, 9(11), 2205-2216; doi:10.3390/ijms9112205
Received: 16 September 2008; in revised form: 31 October 2008 / Accepted: 7 November 2008 / Published: 12 November 2008
Show/Hide Abstract | Cited by 14 | PDF Full-text (124 KB) | HTML Full-text | XML Full-text
abstract graphic
p. 2169-2183
by , , ,  and
Int. J. Mol. Sci. 2008, 9(11), 2169-2183; doi:10.3390/ijms9112169
Received: 19 March 2008; in revised form: 29 October 2008 / Accepted: 31 October 2008 / Published: 7 November 2008
Show/Hide Abstract | Cited by 19 | PDF Full-text (292 KB) | HTML Full-text | XML Full-text
abstract graphic
p. 2127-2145
by
Int. J. Mol. Sci. 2008, 9(11), 2127-2145; doi:10.3390/ijms9112127
Received: 31 July 2008; in revised form: 29 October 2008 / Accepted: 3 November 2008 / Published: 5 November 2008
Show/Hide Abstract | Cited by 37 | PDF Full-text (139 KB) | HTML Full-text | XML Full-text
abstract graphic
p. 2146-2158
by ,  and
Int. J. Mol. Sci. 2008, 9(11), 2146-2158; doi:10.3390/ijms9112146
Received: 17 October 2008; in revised form: 31 October 2008 / Accepted: 4 November 2008 / Published: 5 November 2008
Show/Hide Abstract | Cited by 20 | PDF Full-text (2497 KB) | HTML Full-text | XML Full-text
abstract graphic
p. 2114-2126
by , ,  and
Int. J. Mol. Sci. 2008, 9(11), 2114-2126; doi:10.3390/ijms9112114
Received: 21 July 2008; in revised form: 25 September 2008 / Accepted: 27 September 2008 / Published: 4 November 2008
Show/Hide Abstract | Cited by 14 | PDF Full-text (256 KB) | HTML Full-text | XML Full-text
abstract graphic
p. 2062-2090
by  and
Int. J. Mol. Sci. 2008, 9(11), 2062-2090; doi:10.3390/ijms9112062
Received: 28 July 2008; in revised form: 26 October 2008 / Accepted: 28 October 2008 / Published: 31 October 2008
Show/Hide Abstract | Cited by 45 | PDF Full-text (200 KB) | HTML Full-text | XML Full-text
abstract graphic
p. 2027-2043
by
Int. J. Mol. Sci. 2008, 9(10), 2027-2043; doi:10.3390/ijms9102027
Received: 16 September 2008; in revised form: 27 October 2008 / Accepted: 28 October 2008 / Published: 29 October 2008
Show/Hide Abstract | Cited by 5 | PDF Full-text (737 KB) | XML Full-text
abstract graphic
p. 1915-1926
by , , ,  and
Int. J. Mol. Sci. 2008, 9(10), 1915-1926; doi:10.3390/ijms9101915
Received: 21 August 2008; in revised form: 26 September 2008 / Accepted: 6 October 2008 / Published: 9 October 2008
Show/Hide Abstract | Cited by 5 | PDF Full-text (71 KB) | HTML Full-text | XML Full-text
abstract graphic
p. 1717-1729
by , Jr.,  and
Int. J. Mol. Sci. 2008, 9(9), 1717-1729; doi:10.3390/ijms9091717
Received: 6 August 2008; in revised form: 26 August 2008 / Accepted: 4 September 2008 / Published: 9 September 2008
Show/Hide Abstract | Cited by 11 | PDF Full-text (314 KB) | HTML Full-text | XML Full-text
p. 1676-1684
by  and
Int. J. Mol. Sci. 2008, 9(9), 1676-1684; doi:10.3390/ijms9091676
Received: 27 June 2008; in revised form: 8 August 2008 / Accepted: 29 August 2008 / Published: 2 September 2008
Show/Hide Abstract | Cited by 6 | PDF Full-text (627 KB) | HTML Full-text | XML Full-text
p. 1515-1526
by ,  and
Int. J. Mol. Sci. 2008, 9(8), 1515-1526; doi:10.3390/ijms9081515
Received: 17 April 2008; in revised form: 25 July 2008 / Accepted: 1 August 2008 / Published: 25 August 2008
Show/Hide Abstract | Cited by 5 | PDF Full-text (219 KB) | XML Full-text
p. 1489-1503
by , , , ,  and
Int. J. Mol. Sci. 2008, 9(8), 1489-1503; doi:10.3390/ijms9081489
Received: 13 May 2008; in revised form: 18 July 2008 / Accepted: 18 July 2008 / Published: 22 August 2008
Show/Hide Abstract | Cited by 24 | PDF Full-text (174 KB) | HTML Full-text | XML Full-text
p. 719-735
by  and
Int. J. Mol. Sci. 2008, 9(5), 719-735; doi:10.3390/ijms9050719
Received: 14 January 2008; in revised form: 6 April 2008 / Accepted: 6 May 2008 / Published: 8 May 2008
Show/Hide Abstract | Cited by 14 | PDF Full-text (3617 KB) | HTML Full-text | XML Full-text
p. 578-605
by
Int. J. Mol. Sci. 2008, 9(4), 578-605; doi:10.3390/ijms9040578
Received: 7 December 2007; in revised form: 7 April 2008 / Accepted: 10 April 2008 / Published: 18 April 2008
Show/Hide Abstract | Cited by 11 | PDF Full-text (1020 KB) | HTML Full-text | XML Full-text
p. 554-570
by , , , , , , ,  and
Int. J. Mol. Sci. 2008, 9(4), 554-570; doi:10.3390/ijms9040554
Received: 11 January 2008; in revised form: 19 March 2008 / Accepted: 2 April 2008 / Published: 8 April 2008
Show/Hide Abstract | Cited by 16 | PDF Full-text (226 KB) | HTML Full-text | XML Full-text
p. 394-400
by , ,  and
Int. J. Mol. Sci. 2008, 9(3), 394-400; doi:10.3390/ijms9030394
Received: 11 January 2008; in revised form: 18 February 2008 / Accepted: 18 March 2008 / Published: 20 March 2008
Show/Hide Abstract | Cited by 6 | PDF Full-text (95 KB) | HTML Full-text | XML Full-text
Select/unselect all
Displaying article 1-34
Select articles Export citation of selected articles as:

Last update: 26 February 2014

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert