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Int. J. Mol. Sci. 2009, 10(1), 147-173; doi:10.3390/ijms10010147

Trichothecenes in Cereal Grains

1 Lethbridge Research Centre, Agriculture and Agri-Food Canada, 5403 1st Avenue South, Lethbridge, AB, Canada T1J 4B1 2 Michael Smith Laboratories, The University of British Columbia, #301 - 2185 East Mall, Vancouver, B.C., Canada V6T 1Z4
* Author to whom correspondence should be addressed.
Received: 7 November 2008 / Revised: 16 December 2008 / Accepted: 5 January 2009 / Published: 6 January 2009
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Trichothecenes are sesquiterpenoid mycotoxins associated with fusarium head blight (FHB) of cereals, with worldwide economic and health impacts. While various management strategies have been proposed to reduce the mycotoxin risk, breeding towards FHB-resistance appears to be the most effective means to manage the disease, and reduce trichothecene contamination of cereal-based food products. This review provides a brief summary of the trichothecene synthesis in Fusarium species, their toxicity in plants and humans, followed by the current methods of screening and breeding for resistance to FHB and trichothecene accumulation.
Keywords: Trichothecene; fusarium head blight; cereal grain Trichothecene; fusarium head blight; cereal grain
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Foroud, N.A.; Eudes, F. Trichothecenes in Cereal Grains. Int. J. Mol. Sci. 2009, 10, 147-173.

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Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert