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Int. J. Mol. Sci. 2008, 9(11), 2169-2183; doi:10.3390/ijms9112169

Survey of Slaughtered Pigs for Occurrence of Ochratoxin A and Porcine Nephropathy in Serbia

1,* , 2
1, 3
1 Institute of Meat Hygiene and Technology, Kaćanskog 13, 11000 Belgrade, Serbia 2 Department for Animal Sciences, Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 10, 21000 Novi Sad, Serbia 3 Department of Pathomorphology, Faculty of Veterinary Medicine, University of Belgrade, Bulevar Oslobođenja 18, 11000 Beograd, Serbia
* Author to whom correspondence should be addressed.
Received: 19 March 2008 / Revised: 29 October 2008 / Accepted: 31 October 2008 / Published: 7 November 2008
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Samples of blood, kidney and liver were randomly selected from slaughtered pigs (n=90) and analyzed for ochratoxin A by HPLC. In addition, in order to obtain information on the occurrence of nephropathy, histological examinations were carried out. Of the 90 liver samples, 26.6% contained OTA in the range of 0.22-14.5 ng/g. The incidence of OTA in serum and kidney were very similar (31%, 33.3%), with a maximum concentration of 220.8 ng/mL, and 52.5 ng/g, respectively. Histopathological examination of kidneys confirmed tubulopathies with edema and cell vacuolization. In addition, hemorrhages and necrosis of proximal kidney tubules’ cells were found.
Keywords: Ochratoxin A; pig; tissues; nephropathy Ochratoxin A; pig; tissues; nephropathy
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Milićević, D.; Jurić, V.; Stefanović, S.; Jovanović, M.; Janković, S. Survey of Slaughtered Pigs for Occurrence of Ochratoxin A and Porcine Nephropathy in Serbia. Int. J. Mol. Sci. 2008, 9, 2169-2183.

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