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Int. J. Mol. Sci. 2008, 9(11), 2169-2183; doi:10.3390/ijms9112169
Article

Survey of Slaughtered Pigs for Occurrence of Ochratoxin A and Porcine Nephropathy in Serbia

1,* , 2
,
1, 3
 and
1
1 Institute of Meat Hygiene and Technology, Kaćanskog 13, 11000 Belgrade, Serbia 2 Department for Animal Sciences, Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 10, 21000 Novi Sad, Serbia 3 Department of Pathomorphology, Faculty of Veterinary Medicine, University of Belgrade, Bulevar Oslobođenja 18, 11000 Beograd, Serbia
* Author to whom correspondence should be addressed.
Received: 19 March 2008 / Revised: 29 October 2008 / Accepted: 31 October 2008 / Published: 7 November 2008
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Abstract

Samples of blood, kidney and liver were randomly selected from slaughtered pigs (n=90) and analyzed for ochratoxin A by HPLC. In addition, in order to obtain information on the occurrence of nephropathy, histological examinations were carried out. Of the 90 liver samples, 26.6% contained OTA in the range of 0.22-14.5 ng/g. The incidence of OTA in serum and kidney were very similar (31%, 33.3%), with a maximum concentration of 220.8 ng/mL, and 52.5 ng/g, respectively. Histopathological examination of kidneys confirmed tubulopathies with edema and cell vacuolization. In addition, hemorrhages and necrosis of proximal kidney tubules’ cells were found.
Keywords: Ochratoxin A; pig; tissues; nephropathy Ochratoxin A; pig; tissues; nephropathy
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Milićević, D.; Jurić, V.; Stefanović, S.; Jovanović, M.; Janković, S. Survey of Slaughtered Pigs for Occurrence of Ochratoxin A and Porcine Nephropathy in Serbia. Int. J. Mol. Sci. 2008, 9, 2169-2183.

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