Next Article in Journal / Special Issue
Analysis of Mechanisms of T-2 Toxin Toxicity Using Yeast DNA Microarrays
Previous Article in Journal
Some Properties of Composite Panels Made from Wood Flour and Recycled Polyethylene
Previous Article in Special Issue
Species-specific Fungal DNA in Airborne Dust as Surrogate for Occupational Mycotoxin Exposure?
Int. J. Mol. Sci. 2008, 9(12), 2570-2584; doi:10.3390/ijms9122570

Zearalenone and Reproductive Function in Farm Animals

1,*  and 2
1 Institute of Sciences of Food Production (ISPA), National Research Council (CNR)/ Via G. Amendola 122/O, 70125 Bari, Italy 2 Department of Animal Production, University of Bari / Strada Provinciale Casamassima Km3, 70100 Valenzano, Italy
* Author to whom correspondence should be addressed.
Received: 3 November 2008 / Revised: 4 December 2008 / Accepted: 8 December 2008 / Published: 11 December 2008
View Full-Text   |   Download PDF [169 KB, uploaded 19 June 2014]   |  


Farm animals are exposed to zearalenone through the feed because of the widespread occurrence of this mycotoxin in cereals and clinical reproductive disorders due to mycotoxin effects are often reported in farm animal species. This review describes the metabolism, the mechanistic aspects, the clinical reproductive symptoms and the in vitro effects on functional parameters of oocytes and sperm cells induced by zearalenone and its derivatives in farm animals. The studies on in vitro effects allow to understand the action mechanisms of mycotoxins and, sometime, to explain the in vivo symptoms. The impairment of semen quality and female reproductive function induced by zearalenone could be a factor responsible for the reproductive failure in farm animals.
Keywords: Zearalenone and its derivatives; farm animals; in vivo; in vitro Zearalenone and its derivatives; farm animals; in vivo; in vitro
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
MDPI and ACS Style

Minervini, F.; Dell’Aquila, M.E. Zearalenone and Reproductive Function in Farm Animals. Int. J. Mol. Sci. 2008, 9, 2570-2584.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert