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Int. J. Mol. Sci. 2008, 9(12), 2357-2365; doi:10.3390/ijms9122357

Growth and Mycotoxin Production by Chaetomium globosum Is Favored in a Neutral pH

1
Department of Microbiology and Immunology, Texas Tech University Health Sciences Center 3601 4th Street Mail stop 6591 Lubbock, TX 79430, USA
2
Department of Internal Medicine, Texas Tech University Health Sciences Center 3601 4th Street Mail stop 6591 Lubbock, TX 79430, USA
*
Author to whom correspondence should be addressed.
Received: 17 September 2008 / Revised: 31 October 2008 / Accepted: 25 November 2008 / Published: 26 November 2008
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Abstract

Chaetomium globosum is frequently isolated in water-damaged buildings and produces two mycotoxins called chaetoglobosins A and C when cultured on building material. In this study, the influence of ambient pH on the growth of C. globosum was examined on an artificial medium. This fungus was capable of growth on potato dextrose agar ranging in pH from 4.3 to 9.4 with optimal growth and chaetoglobosin C production occurring at a neutral pH. In addition, our results show that sporulation is favored in an acidic environment.
Keywords: Ambient pH; chaetoglobosin; Chaetomium globosum; indoor air quality; mycotoxin Ambient pH; chaetoglobosin; Chaetomium globosum; indoor air quality; mycotoxin
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Fogle, M.R.; Douglas, D.R.; Jumper, C.A.; Straus, D.C. Growth and Mycotoxin Production by Chaetomium globosum Is Favored in a Neutral pH. Int. J. Mol. Sci. 2008, 9, 2357-2365.

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Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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