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Int. J. Mol. Sci. 2008, 9(12), 2474-2494; doi:10.3390/ijms9122474
Review

Mycotoxin Detection Plays “Cops and Robbers”: Cyclodextrin Chemosensors as Specialized Police?

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Received: 29 September 2008 / Revised: 20 November 2008 / Accepted: 3 December 2008 / Published: 5 December 2008
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Abstract

As in a cops and robbers play we discover new mycotoxins and metabolites everyday and we are forced to develop new molecules quickly as chemo- or biosensors or to modify existing molecules able to recognize these new hazardous compounds. This will result in an enormous cost saving to agro-food industry through the prevention and reduction of product recalls and reduced treatment costs. Here we present a brief review of the rapid methods used to detect mycotoxins, considering usefulness and limits. Then we propose a new fast, efficient and cheap methodology, based on a combination of computer chemistry aided design and fluorescence, that can help to drive synthesis in a more efficient way.
Keywords: Chemosensing; fluorescence; docking; molecular engineering Chemosensing; fluorescence; docking; molecular engineering
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Cozzini, P.; Ingletto, G.; Singh, R.; Dall’Asta, C. Mycotoxin Detection Plays “Cops and Robbers”: Cyclodextrin Chemosensors as Specialized Police? Int. J. Mol. Sci. 2008, 9, 2474-2494.

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