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Int. J. Mol. Sci. 2008, 9(12), 2474-2494; doi:10.3390/ijms9122474
Review

Mycotoxin Detection Plays “Cops and Robbers”: Cyclodextrin Chemosensors as Specialized Police?

1,2,* , 1
,
1
 and
3
1 Molecular Modeling Laboratory, Department of General and Inorganic Chemistry, University of Parma, Via G.P. Usberti 17/A 43100, Parma, Italy 2 INBB, National Institute for Biostructures and Biosystems, Viale Medaglie d’oro 305, 00136 Rome, Italy 3 Department of Organic and Industrial Chemistry, University of Parma, Via G.P. Usberti 17/A 43100, Parma, Italy
* Author to whom correspondence should be addressed.
Received: 29 September 2008 / Revised: 20 November 2008 / Accepted: 3 December 2008 / Published: 5 December 2008
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Abstract

As in a cops and robbers play we discover new mycotoxins and metabolites everyday and we are forced to develop new molecules quickly as chemo- or biosensors or to modify existing molecules able to recognize these new hazardous compounds. This will result in an enormous cost saving to agro-food industry through the prevention and reduction of product recalls and reduced treatment costs. Here we present a brief review of the rapid methods used to detect mycotoxins, considering usefulness and limits. Then we propose a new fast, efficient and cheap methodology, based on a combination of computer chemistry aided design and fluorescence, that can help to drive synthesis in a more efficient way.
Keywords: Chemosensing; fluorescence; docking; molecular engineering Chemosensing; fluorescence; docking; molecular engineering
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Cozzini, P.; Ingletto, G.; Singh, R.; Dall’Asta, C. Mycotoxin Detection Plays “Cops and Robbers”: Cyclodextrin Chemosensors as Specialized Police? Int. J. Mol. Sci. 2008, 9, 2474-2494.

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