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Impact of Deoxynivalenol on the Intestinal Microflora of Pigs
French Agency for Food Safety (AFSSA) – Zoopôle des côtes d’Armor, BP53, 22440 Ploufragan – France
French Institute of Agricultural Research (INRA) – UR 66- Unité de Pharmacologie-Toxicologie, 180 chemin de Tournefeuille, 31027 Toulouse cedex 3 – France
* Author to whom correspondence should be addressed.
Received: 6 November 2008; in revised form: 22 December 2008 / Accepted: 24 December 2008 / Published: 27 December 2008
Abstract: Deoxynivalenol (DON), a mycotoxin produced by some Fusarium species, is a frequent contaminant of cereal. In the present study, 24 weanling piglets received either control feed or feed naturally contaminated with DON (2.8 mg/kg) for four weeks. Consumption of contaminated feed significantly reduced the animal weight gain during the first week of the experiment, but had a moderate effect on cultivable bacteria in the pig intestine. By contrast, changes in the intestinal microflora were observed by Capillary Electrophoresis Single-Stranded Conformation Polymorphism (CE-SSCP) in DON-exposed animals, suggesting an impact of this toxin on the dynamics of intestinal bacteria communities.
Keywords: Mycotoxin; Deoxynivalenol; pigs; intestinal microflora; growth performance; faeces; anaerobic sulfite-reducing bacteria; CE-SSCP
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MDPI and ACS Style
Waché, Y.J.; Valat, C.; Postollec, G.; Bougeard, S.; Burel, C.; Oswald, I.P.; Fravalo, P. Impact of Deoxynivalenol on the Intestinal Microflora of Pigs. Int. J. Mol. Sci. 2009, 10, 1-17.
Waché YJ, Valat C, Postollec G, Bougeard S, Burel C, Oswald IP, Fravalo P. Impact of Deoxynivalenol on the Intestinal Microflora of Pigs. International Journal of Molecular Sciences. 2009; 10(1):1-17.
Waché, Yann J.; Valat, Charlotte; Postollec, Gilbert; Bougeard, Stephanie; Burel, Christine; Oswald, Isabelle P.; Fravalo, Philippe. 2009. "Impact of Deoxynivalenol on the Intestinal Microflora of Pigs." Int. J. Mol. Sci. 10, no. 1: 1-17.