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Keywords = vertebra landmark detection

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17 pages, 2548 KB  
Article
A Dual Coordinate System Vertebra Landmark Detection Network with Sparse-to-Dense Vertebral Line Interpolation
by Han Zhang and Albert C. S. Chung
Bioengineering 2024, 11(1), 101; https://doi.org/10.3390/bioengineering11010101 - 22 Jan 2024
Cited by 5 | Viewed by 3044
Abstract
Precise surveillance and assessment of spinal disorders are important for improving health care and patient survival rates. The assessment of spinal disorders, such as scoliosis assessment, depends heavily on precise vertebra landmark localization. However, existing methods usually search for only a handful of [...] Read more.
Precise surveillance and assessment of spinal disorders are important for improving health care and patient survival rates. The assessment of spinal disorders, such as scoliosis assessment, depends heavily on precise vertebra landmark localization. However, existing methods usually search for only a handful of keypoints in a high-resolution image. In this paper, we propose the S2D-VLI VLDet network, a unified end-to-end vertebra landmark detection network for the assessment of scoliosis. The proposed network considers the spatially relevant information both from inside and between vertebrae. The new vertebral line interpolation method converts the training labels from sparse to dense, which can improve the network learning process and method performance. In addition, through the combined use of the Cartesian and polar coordinate systems in our method, the symmetric mean absolute percentage error (SMAPE) in scoliosis assessment can be reduced substantially. Specifically, as shown in the experiments, the SMAPE value decreases from 9.82 to 8.28. The experimental results indicate that our proposed approach is beneficial for estimating the Cobb angle and identifying landmarks in X-ray scans with low contrast. Full article
(This article belongs to the Section Biosignal Processing)
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11 pages, 3728 KB  
Article
SpineHRformer: A Transformer-Based Deep Learning Model for Automatic Spine Deformity Assessment with Prospective Validation
by Moxin Zhao, Nan Meng, Jason Pui Yin Cheung, Chenxi Yu, Pengyu Lu and Teng Zhang
Bioengineering 2023, 10(11), 1333; https://doi.org/10.3390/bioengineering10111333 - 20 Nov 2023
Cited by 14 | Viewed by 3177
Abstract
The Cobb angle (CA) serves as the principal method for assessing spinal deformity, but manual measurements of the CA are time-consuming and susceptible to inter- and intra-observer variability. While learning-based methods, such as SpineHRNet+, have demonstrated potential in automating CA measurement, their accuracy [...] Read more.
The Cobb angle (CA) serves as the principal method for assessing spinal deformity, but manual measurements of the CA are time-consuming and susceptible to inter- and intra-observer variability. While learning-based methods, such as SpineHRNet+, have demonstrated potential in automating CA measurement, their accuracy can be influenced by the severity of spinal deformity, image quality, relative position of rib and vertebrae, etc. Our aim is to create a reliable learning-based approach that provides consistent and highly accurate measurements of the CA from posteroanterior (PA) X-rays, surpassing the state-of-the-art method. To accomplish this, we introduce SpineHRformer, which identifies anatomical landmarks, including the vertices of endplates from the 7th cervical vertebra (C7) to the 5th lumbar vertebra (L5) and the end vertebrae with different output heads, enabling the calculation of CAs. Within our SpineHRformer, a backbone HRNet first extracts multi-scale features from the input X-ray, while transformer blocks extract local and global features from the HRNet outputs. Subsequently, an output head to generate heatmaps of the endplate landmarks or end vertebra landmarks facilitates the computation of CAs. We used a dataset of 1934 PA X-rays with diverse degrees of spinal deformity and image quality, following an 8:2 ratio to train and test the model. The experimental results indicate that SpineHRformer outperforms SpineHRNet+ in landmark detection (Mean Euclidean Distance: 2.47 pixels vs. 2.74 pixels), CA prediction (Pearson correlation coefficient: 0.86 vs. 0.83), and severity grading (sensitivity: normal-mild; 0.93 vs. 0.74, moderate; 0.74 vs. 0.77, severe; 0.74 vs. 0.7). Our approach demonstrates greater robustness and accuracy compared to SpineHRNet+, offering substantial potential for improving the efficiency and reliability of CA measurements in clinical settings. Full article
(This article belongs to the Special Issue Artificial Intelligence in Auto-Diagnosis and Clinical Applications)
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25 pages, 13125 KB  
Article
Part Affinity Fields and CoordConv for Detecting Landmarks of Lumbar Vertebrae and Sacrum in X-ray Images
by Chang-Hyeon An, Jeong-Sik Lee, Jun-Su Jang and Hyun-Chul Choi
Sensors 2022, 22(22), 8628; https://doi.org/10.3390/s22228628 - 9 Nov 2022
Cited by 9 | Viewed by 5172
Abstract
With the prevalence of degenerative diseases due to the increase in the aging population, we have encountered many spine-related disorders. Since the spine is a crucial part of the body, fast and accurate diagnosis is critically important. Generally, clinicians use X-ray images to [...] Read more.
With the prevalence of degenerative diseases due to the increase in the aging population, we have encountered many spine-related disorders. Since the spine is a crucial part of the body, fast and accurate diagnosis is critically important. Generally, clinicians use X-ray images to diagnose the spine, but X-ray images are commonly occluded by the shadows of some bones, making it hard to identify the whole spine. Therefore, recently, various deep-learning-based spinal X-ray image analysis approaches have been proposed to help diagnose the spine. However, these approaches did not consider the characteristics of frequent occlusion in the X-ray image and the properties of the vertebra shape. Therefore, based on the X-ray image properties and vertebra shape, we present a novel landmark detection network specialized in lumbar X-ray images. The proposed network consists of two stages: The first step detects the centers of the lumbar vertebrae and the upper end plate of the first sacral vertebra (S1), and the second step detects the four corner points of each lumbar vertebra and two corner points of S1 from the image obtained in the first step. We used random spine cutout augmentation in the first step to robustify the network against the commonly obscured X-ray images. Furthermore, in the second step, we used CoordConv to make the network recognize the location distribution of landmarks and part affinity fields to understand the morphological features of the vertebrae, resulting in more accurate landmark detection. The proposed network was evaluated using 304 X-ray images, and it achieved 98.02% accuracy in center detection and 8.34% relative distance error in corner detection. This indicates that our network can detect spinal landmarks reliably enough to support radiologists in analyzing the lumbar X-ray images. Full article
(This article belongs to the Special Issue Advances of Deep Learning in Medical Image Interpretation)
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14 pages, 6919 KB  
Article
Automated Detection of Ear Tragus and C7 Spinous Process in a Single RGB Image—A Novel Effective Approach
by Ivanna Kramer, Sabine Bauer and Anne Matejcek
BioMedInformatics 2022, 2(2), 318-331; https://doi.org/10.3390/biomedinformatics2020020 - 8 Jun 2022
Cited by 1 | Viewed by 4019
Abstract
Biophotogrammetric methods for postural analysis have shown effectiveness in the clinical practice because they do not expose individuals to radiation. Furthermore, valid statements can be made about postural weaknesses. Usually, such measurements are collected via markers attached to the subject’s body, which can [...] Read more.
Biophotogrammetric methods for postural analysis have shown effectiveness in the clinical practice because they do not expose individuals to radiation. Furthermore, valid statements can be made about postural weaknesses. Usually, such measurements are collected via markers attached to the subject’s body, which can provide conclusions about the current posture. The craniovertebral angle (CVA) is one of the recognized measurements used for the analysis of human head–neck postures. This study presents a novel method to automate the detection of the landmarks that are required to determine the CVA in RGBs. Different image processing methods are applied together with a neuronal network Openpose to find significant landmarks in a photograph. A prominent key body point is the spinous process of the cervical vertebra C7, which is often visible on the skin. Another visual landmark needed for the calculation of the CVA is the ear tragus. The methods proposed for the automated detection of the C7 spinous process and ear tragus are described and evaluated using a custom dataset. The results indicate the reliability of the proposed detection approach, particularly head postures. Full article
(This article belongs to the Special Issue Feature Papers in Medical Statistics and Data Science Section)
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18 pages, 14299 KB  
Article
Automated Cobb Angle Measurement for Adolescent Idiopathic Scoliosis Using Convolutional Neural Network
by Wahyu Caesarendra, Wahyu Rahmaniar, John Mathew and Ady Thien
Diagnostics 2022, 12(2), 396; https://doi.org/10.3390/diagnostics12020396 - 3 Feb 2022
Cited by 45 | Viewed by 13607
Abstract
The Cobb angle measurement of the scoliotic spine is prone to inter- and intra-observer variations in the clinical setting. This paper proposes a deep learning architecture for detecting spine vertebrae from X-ray images to evaluate the Cobb angle automatically. The public AASCE MICCAI [...] Read more.
The Cobb angle measurement of the scoliotic spine is prone to inter- and intra-observer variations in the clinical setting. This paper proposes a deep learning architecture for detecting spine vertebrae from X-ray images to evaluate the Cobb angle automatically. The public AASCE MICCAI 2019 anterior-posterior X-ray image dataset and local images were used to train and test the proposed convolutional neural network architecture. Sixty-eight landmark features of the spine were detected from the input image to obtain seventeen vertebrae on the spine. The vertebrae locations obtained were processed to automatically measure the Cobb angle. The proposed method can measure the Cobb angle with accuracies up to 93.6% and has excellent reliability compared to clinicians’ measurement (intraclass correlation coefficient > 0.95). The proposed deep learning architecture may be used as a tool to augment Cobb angle measurement in X-ray images of patients with adolescent idiopathic scoliosis in a real-world clinical setting. Full article
(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
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