Open AccessCommunication
Antibody Response to Toscana Virus and Sandfly Fever Sicilian Virus in Cats Naturally Exposed to Phlebotomine Sand Fly Bites in Portugal
by
André Pereira, Nazli Ayhan, José Manuel Cristóvão, Hugo Vilhena, Ângela Martins, Patrícia Cachola, Joaquim Henriques, Mónica Coimbra, Ana Catarino, Tereza Lestinova, Tatiana Spitzova, Petr Volf, Lenea Campino, Remi Charrel and Carla Maia
Cited by 13 | Viewed by 3172
Abstract
Phlebotomine sand fly-borne pathogens such as
Leishmania spp. and phleboviruses are emerging threats to humans and animals worldwide. The aim of this work was to evaluate the exposure of cats from Portugal to Toscana virus (TOSV) and Sandfly Fever Sicilian virus (SFSV) and
[...] Read more.
Phlebotomine sand fly-borne pathogens such as
Leishmania spp. and phleboviruses are emerging threats to humans and animals worldwide. The aim of this work was to evaluate the exposure of cats from Portugal to Toscana virus (TOSV) and Sandfly Fever Sicilian virus (SFSV) and assess the associated risk factors. The possible association between exposure to
Phlebotomus perniciosus saliva with TOSV and SFSV was also investigated. Out of 369 cats tested, 18 (4.9%,
n = 365) were seropositive for TOSV, and eight (2.2%,
n = 367) were seropositive for SFSV. Multivariate logistic regression analysis showed that cats presenting clinical signs that were compatible with leishmaniosis and antibodies to TOSV had a significantly higher risk of being SFSV seropositive. The presence of antibodies to sand fly-borne viruses in cats indicate that these animals are frequently exposed to sand flies and transmitted pathogens. Data suggest that cats can be used to qualitatively monitor human exposure to TOSV and SFSV in endemic areas. The clinical impact of SFSV in cats’ health should be investigated. The identification of the sand fly species responsible for the circulation of TOSV and SFSV in nature and the evaluation of the vectorial competence of
P. perniciosus to SFSV should also be addressed.
Full article
