Search Results (121)

Health education programs are important interventions aimed at the acquisition of health knowledge and behaviors that are necessary throughout the lives of individuals of all ages. Considering the importance of health education in structuring the health of the society, it is very important that health education responds to the needs of society and meets its expectations. At this point, public health is protected by providing access to families and communities through health education. In this context, a needs analysis study was conducted with families (students and parents) to establish a health education framework. The study group consisted of 289 volunteer primary and secondary school students and 60 parents who agreed to participate in the study. Semi-structured interviews were conducted with students and parents using a descriptive approach. The needs analysis form prepared by the researchers was used in the interviews and content analysis was applied to the obtained data. The qualitative data obtained from the analyses were interpreted. As a result of the study, it was found that families have expectations and needs in first aid and daily life behaviors (nutrition, hygiene, oral health and diseases) in school health education, and accordingly, school health education can be focused on these specified areas. The fact that families found health knowledge insufficient and considered health education important emphasizes the importance of the knowledge provided by health education and the results. The family health education views obtained in the study can be used in future studies to improve family health behaviors and community health. In addition, family-based school health education can be disseminated with contemporary interventions. Full article

Medicinal plants remain vital in the Phu Tai community in Amnat Charoen in Thailand. Traditional healers’ knowledge is largely undocumented in the literature. Our objective was to document their medicinal plant practices to preserve this valuable knowledge. Our informants were 15 Phu Tai healers. We calculated use values (UV), family importance values (FIV), and informant agreement ratios (IAR) to gauge the significance of the 211 medicinal plants used by the healers. The most important plant families were Fabaceae and Zingiberaceae (FIV = 93). Kha min (Curcuma longa) was the most important medicinal species (UV = 0.66). The decoction was the most common preparation method (85%). Skin/subcutaneous cellular tissue disorders had the highest informant agreement ratio (IAR = 0.73). Shrubs were the most common life form (36%) among the medicinal plants; the majority were collected from community forests (51%) and were native to Thailand (86%). The most frequently used plant part for medicine was the leaf (27%). Medicinal plants that can be purchased were Ueang mai na (Hellenia speciosa), Thep tharo (Cinnamomum parthenoxylon), and Som khon (Talinum paniculatum). Interestingly, monks served as traditional healers. The healer’s age and education were not correlated with the number of medicinal plants they knew. The Amnat Charoen healers possess a rich traditional knowledge of medicinal plants. The information reported here is invaluable for further research in the field of cross-cultural ethnobotany and ethnopharmacology. Full article

Chitooligosaccharides (COSs) are a class of functional carbohydrates with significant application prospects in food and medicine. Chitosanase CsnMY002 from the GH46 family has been used to prepare COS with controlled degrees of polymerization. To enhance the industrial applicability of CsnMY002, molecular dynamics (MD) simulations were applied to investigate the structure–property relationship. Guided by the simulation results, the beneficial mutants were screened through a synergistic strategy using a residue-folding free energy calculation and consensus sequence analysis. Iterative combinations constructed the mutant Mut6 (A49G/K70A/S84A/N89G/D199R/N221G) with significantly improved thermal stability, which had a half-life (t_1/2 value) at 55 °C and 75 °C that was 1.80 and 1.62 times higher than that of the wild type, respectively. A highly active mutant, Mut2, was created, exhibiting a 1.52 times catalytic efficiency of the wild type. An MD simulation analysis of the mutants suggested that the improved enzymatic properties were highly correlated with changes in the dynamic behaviours of the enzyme structure. This study generated more suitable CsnMY002 variants for COS production and provided a comprehensive strategy for the optimization of other industrial enzymes with application potential. Full article

There is a global veterinary workforce shortage, particularly in rural and regional areas. In response to this shortage in New South Wales (NSW), the State Parliament launched a Parliamentary Inquiry in 2023. The Inquiry received 205 publicly available written submissions, providing insights into the perceived challenges and barriers for veterinarians working in rural practice, and how the perceived impact of the feminisation of the workforce interacts with this. By analysing a subset of submissions written by veterinarians reporting lived experiences in rural practice (n = 63), we identified eight major themes. These were as follows: rural practices are not financially sustainable; rural veterinarians often have a more challenging and higher workload than their urban counterparts; working in rural practice increases challenges to health and wellbeing; it is difficult to recruit and retain people in rural practice; veterinary students are poorly selected and not well prepared for rural practice; clients have unrealistic expectations of rural veterinarians; rural practice is not compatible with family life; and veterinarians have mixed opinions regarding whether an increase in the proportion of female veterinarians is a key contributing factor in the shortage of veterinarians. These findings may assist in the development of recruitment and retention strategies for rural veterinary practice. Full article

Background/Objectives: Given the observed increase in life expectancy within Europe, it is anticipated that there will be a growing number of retirees and a lengthening of the retirement phase for individuals. This has brought attention to the examination of how the disengagement from professional endeavors influences overall wellbeing. The objective of this investigation was to conduct a comprehensive literature review spanning the period from 1998 to 2024, focusing on the intersection of retirement and wellbeing. Methods: This review (PROSPERO reference: CRD42024621454) was based on scientific articles available in PsycInfo, PubMed, Scopus, SPORTDiscus, and Web of Science, resulting in the inclusion of 32 articles in the systematic review, of which 12 were eligible for meta-analysis. The quality of evidence was evaluated based on the Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies checklist. Results: The meta-analysis results revealed that the observed effect size was d = 0.383, considered moderate. This value was statistically significant (Z = 3.197; p = 0.001) with a 95% CI [0.148, 0.617]. The publications were subjected to qualitative analysis, taking into account study type and thematic content. The discernible outcomes were categorized as follows: (1) expectations regarding retirement, (2) preparation for retirement, (3) family relations and grandparenting, (4) quality of life and satisfaction with retirement, and (5) health consequences of retirement. Conclusions: The prevalent approach predominantly comprised quantitative investigations, with a particular focus on exploring the nexus between retirement and health implications, particularly in the context of European participants. This emphasis on health consequences provides a deeper comprehension of this association. Full article

Background: Technological advancement has evolved dynamics in the pace of day-to-day life. Economic and social development has introduced new meanings at individual and societal levels. Modernity and development have transformed the social fabric and relationships. Social media has instigated a tremendous multifaceted transformation in lifestyle. An increase in disposable income from prepared food, especially contemporary cuisines, has evolved diversified changes in consumers’ behavior. These changes include trends, perceptions, consumption patterns, and modes of fast food (quality, quantity, tastes), including delivery systems, among all age groups and genders. This study investigated the factors that influence food choices towards contemporary cuisine, the influence of contemporary cuisine food choice on homemade/traditional foods, and how food choices of contemporary cuisines affect family ties. Methods: In this exploratory study, a cross-sectional quantitative survey research method was used to obtain the insights of youths. A systematic random sampling procedure was adopted. We recruited at a public sector university of Lahore, namely, the Institute of Social and Cultural Studies, University of the Punjab. The sample size was 260. We used modified versions of the Food Frequency Questionnaire and the Food Choice Questionnaire to assess the food choices of contemporary cuisine, homemade/traditional food, and family ties. The Cronbach’s coefficient alpha level varied from 0.62 to 0.85 among scales. We performed descriptive and inferential statistics (factor analysis and multivariate regression analysis) by using SPSS 23. Results: Age and education showed a significant relationship with traditional food. Taste was the only factor identified for food choices of contemporary cuisine. Traditional food and family ties were the factors identified in the analysis. Conclusions: Food choices of contemporary cuisines were found to be just for good taste and fun. Homemade food regulates the traditions of traditional food. Cooking and dinning together not only maintained the food choices but also encourage and motivate the connectedness and closeness that strengthen family ties. Full article

This paper examines the formative influence of Jesus’ upbringing in Nazareth, particularly as depicted in Luke 4: 16–22, alongside related passages such as Luke 2: 51–52. Through these accounts, this analysis seeks to elucidate the social, cultural, and spiritual dimensions of Jesus’ early life and their significance in shaping his mission and identity, as well as how his religious customs and community involvement can inspire contemporary youth by integrating the core pillars of faith, education, and family and empowering them to confront modern challenges with a holistic perspective inspired by Jesus’ mission. Methodologically, it should be taken for granted that a tendency to psychologise biblical characters—interpreting their actions or decisions as if they shared modern psychological frameworks—can lead to oversimplifications or misapplications. For example, Jesus’ obedience to his parents reflects a culture of strict family authority, contrasting with today’s focus on independence and self-expression in youth development. By examining key Greek terms such as tethramménos (from trépho: ‘having been brought up’) and katà tò eiōthòs autộ (‘as was his custom’) in v.16, this study emphasises Jesus’ strong connection to his faith and cultural heritage. His regular participation in synagogue life and his upbringing in a religious and familial context (see Luke 2: 51–52) were crucial in shaping his identity and preparing him for his transformative and transforming mission, according to the Isaianic prophecy (61: 1–2) he read on the same occasion. This paper argues that these early experiences, particularly his education within the Jewish tradition and his family’s role in nurturing his spiritual growth, were foundational for the holistic mission Jesus would later proclaim—a mission that sought spiritual, social, and physical liberation. Full article

Individuals with spinal cord injury (SCI) experience an increased risk for obesity and cardiometabolic disease. Recommendations to prevent and treat obesity for those with SCI follow those of the US Department of Agriculture to adopt a healthy eating pattern that includes eating a variety of fruits, vegetables, grains, dairy, and protein, plus limiting added sugars, saturated fats, and sodium. Yet, people with SCI eat too many calories, fat, and carbohydrates and too few fruits, vegetables, and whole grains. The study is based on secondary analyses of SCI participants (n = 122) who enrolled in a weight loss study to determine how SCI may impact their ability to prepare food at home. We hypothesize those with higher-level spinal injuries (specifically, those with cervical versus those with thoracic or lumbar/sacral injuries) experience significantly greater difficulty and are more likely to rely on others’ assistance to perform meal preparation tasks. Physiologic (weight, BMI, blood pressure, hemoglobin A1c) and self-reported data (demographic plus responses to the Life Habits Short Survey and meal prep items) were collected at baseline and qualitative data were obtained from a subsample after the intervention during phone interviews. Participants’ average age was 50 ± 14.7 years old, they lived with SCI for an average of 13.0 ± 13.1 years, and their average BMI was 32.0 ± 6.5. Participants were predominantly white (76.1%) men (54.1%) who had some college education (76.3%), though only 28.8% worked. A substantial proportion of respondents (30% to 68%) reported difficulty across the 13 tasks related to purchasing and preparing meals, with a proxy reported as the most common assistance type used across all tasks (17% to 42%). Forty-nine percent reported difficulty preparing simple meals, with 29% reporting a proxy does the task. More than half reported difficulty using the oven and stove, though between 60% to 70% reported no difficulty using other kitchen appliances (e.g., coffee machine, food processor, can opener), the refrigerator, or microwave. There was a significant difference in kitchen function by injury level. Those living with cervical-level injuries had significantly greater limitations than those with thoracic-level injuries. Spouses, other family members, and caregivers were most likely to serve as proxies and these individuals exerted both positive and negative influences on respondents’ dietary intake, based on qualitative data obtained during interviews. The results suggest that many people living with SCI experience functional and environmental barriers that impact their ability to prepare food and use kitchen appliances. Future research should examine how SCI-related functional limitations, transportation access, accessibility of the kitchen, ability to use appliances, availability of financial resources, and assistance by others to prepare foods impact people’s ability to follow a healthy eating pattern. Full article

Viral haemorrhagic fevers encompass a diverse group of severe, often life-threatening illnesses caused by viruses from multiple families, including Arenaviridae, Filoviridae, Flaviviridae, Hantaviridae, Nairoviridae, Peribunyaviridae, and Phenuiviridae. Characterised by fever and haemorrhagic symptoms, these diseases challenge public health systems by overwhelming healthcare facilities, complicating diagnostic processes, and requiring extensive resources for containment and treatment, especially in resource-limited settings. This discussion explores the intricate relationships between VHFs and their transmission vectors—both animal and arthropod—and examines the impact of ecological and geographic factors on disease spread. The primary transmission of VHFs typically occurs through direct contact with infected animals or via bites from haematophagous arthropods, facilitating zoonotic and, at times, human-to-human transmission. With an emphasis on the role of diverse wildlife, domesticated animals, and vectors such as mosquitoes and ticks in the epidemiology of VHFs, there is a recognised need for robust surveillance and strategic public health responses to manage outbreaks. This review discusses the necessity of interdisciplinary approaches that integrate virology, ecology, and public health to enhance diagnostic capabilities, develop vaccines and antivirals, and improve outbreak interventions. Exploring the ecological and biological dynamics of VHFs will help bolster a deeper understanding of these emerging viruses and underpin preparation for future outbreaks. The importance of enhanced global cooperation, continuous research, and collaboration to mitigate the public health threats posed by these complex infections is a central theme, serving as a foundational strategy to reinforce worldwide preparedness and response efforts. Future directions include addressing gaps in vaccine development and tailoring public health strategies to the unique challenges of managing VHFs, such as the rapid mutation rates of viruses, the need for cold chain logistics for vaccine distribution, and socio-economic barriers to healthcare access, in order to ensure readiness for and effective response to emerging threats worldwide. Full article

Fenugreek (Trigonella foenum-graecum L.) is an annual, dicotyledonous medicinal plant which belongs to the Leguminosae family, and its leaves and seeds are widely used and cultivated throughout the world. Their widespread utilization is attributed to the great variety of primary and secondary metabolites they contain, such as flavonoids, alkaloids, steroidal saponins, tannins, as well as carbohydrates, in particular galactomannan, which is the focus of the current study. The presence of an equal number of galactose and mannose residues (Gal/Man ratio of 1:1) prevents the formation of hydrogen bonds between the mannose ones. This determines the good solubility of fenugreek galactomannan in cold water, even at low concentrations. The water solubility would be significantly better than that of carob and even slightly higher than that of guar gum, precisely due to their structural characteristics, which contribute to their possible advantages. Moreover, it is a good alternative as an excipient for the development of pharmaceutical dosage forms, as well as in the preparation of food products, affecting not only their structure but also their shelf life. Furthermore, it has promising applications not only in the fields of medicine and pharmaceutics but also offers environmental benefits. All of the above-mentioned factors are of high interest and qualify fenugreek galactomannan as a versatile polysaccharide, which is the reason for summarizing its benefits in this review. Full article

Teacher life satisfaction is crucial for their well-being and the educational success of their students, both essential elements for sustainable development. This study identifies the most relevant predictors of life satisfaction among Peruvian teachers using machine learning. We analyzed data from the National Survey of Teachers of Public Basic Education Institutions (ENDO-2020) conducted by the Ministry of Education of Peru, using filtering methods (mutual information, analysis of variance, chi-square, and Spearman’s correlation coefficient) along with embedded methods (Classification and Regression Trees—CART; Random Forest; Gradient Boosting; XGBoost; LightGBM; and CatBoost). Subsequently, we generated machine learning models with Random Forest; XGBoost; Gradient Boosting; Decision Trees—CART; CatBoost; LightGBM; Support Vector Machine; and Multilayer Perceptron. The results reveal that the main predictors of life satisfaction are satisfaction with health, employment in an educational institution, the living conditions that can be provided for their family, and conditions for performing their teaching duties, as well as age, the degree of confidence in the Ministry of Education and the Local Management Unit (UGEL), participation in continuous training programs, reflection on the outcomes of their teaching practice, work–life balance, and the number of hours dedicated to lesson preparation and administrative tasks. Among the algorithms used, LightGBM and Random Forest achieved the best results in terms of accuracy (0.68), precision (0.55), F1-Score (0.55), Cohen’s kappa (0.42), and Jaccard Score (0.41) for LightGBM, and accuracy (0.67), precision (0.54), F1-Score (0.55), Cohen’s kappa (0.41), and Jaccard Score (0.41). These results have important implications for educational management and public policy implementation. By identifying dissatisfied teachers, strategies can be developed to improve their well-being and, consequently, the quality of education, contributing to the sustainability of the educational system. Algorithms such as LightGBM and Random Forest can be valuable tools for educational management, enabling the identification of areas for improvement and optimizing decision-making. Full article

Psoriasis, an immune-mediated inflammatory skin disorder, seriously affects the quality of life of nearly four percent of the world population. Euphorbia helioscopia L. is the monarch constituent of Chinese ZeQi powder preparation for psoriasis, so it is necessary to illustrate its active ingredients. Thus, twenty-three diterpenoids, including seven new ones, were isolated from the whole herb of E. helioscopia L. Compounds 1 and 2, each featuring a 2,3-dicarboxylic functionality, are the first examples in the ent-2,3-sceo-atisane or the ent-2,3-sceo-abietane family. Extensive spectroscopic analysis (1D, 2D NMR, and HRMS data) and computational methods were used to confirm their structures and absolute configurations. According to the previous study and NMR data from the jatropha diterpenes obtained in this study, some efficient ¹H NMR spectroscopic rules for assigning the relative configurations of 3α-benzyloxy-jatroph-11E-ene and 7,8-seco-3α-benzyloxy-jatropha-11E-ene were summarized. Moreover, the hyperproliferation of T cells and keratinocytes is considered a key pathophysiology of psoriasis. Anti-proliferative activities against induced T/B lymphocytes and HaCaT cells were tested, and IC₅₀ values of some compounds ranged from 6.7 to 31.5 μM. Compounds 7 and 11 reduced the secretions of IFN-γ and IL-2 significantly. Further immunofluorescence experiments and a docking study with NF-κB P65 showed that compound 13 interfered with the proliferation of HaCaT cells by inhibiting the NF-κB P65 phosphorylation at the protein level. Full article

The rationale for this research is the investigation of the potential health benefits as well as the antibacterial and antifungal properties of selected aromatic plants from the Lamiaceae family, which may lead to the development of improved functional foods. The present study investigated the effects of incorporating dried aromatic plants Thymus vulgaris, Thymus serpyllum, Thymus × citriodorus, Origanum vulgare and Rosmarinus officinalis at a concentration of 1% in refined wheat flour and wholemeal flour on the production of functional tortillas. Sensory analysis was employed to identify the optimal 1% addition, with the objective of achieving a favorable flavor and aroma profile. It was hypothesized that this addition would affect water activity, moisture, texture, color, antioxidant content and phenolic content, thereby enhancing the tortillas as a source of bioactive compounds. The results indicated that the type of flour used had a significant impact on the water activity of the tortillas, with wholemeal flour resulting in higher water activity than refined flour. The water activity ranged between 0.735 and 0.821, while the water content remained relatively stable. The water activity in whole-grain tortillas was significantly higher than that of refined flour tortillas, with a value exceeding 0.8, which makes them susceptible to mold growth and the production of mycotoxins. The sensory evaluations indicated that the enriched refined flour tortillas with common thyme (Thymus vulgaris), lemon thyme (Thymus × citriodorus) and rosemary (Rosmarinus officinalis) were rated highly; a similar result was observed for the whole-grain tortillas enriched with wild thyme (Thymus serpyllum) and lemon thyme. The whole-grain tortillas with rosemary were rated the highest of all the tortillas. The addition of aromatic plants increased the phenolic content and the antioxidant potential, depending on the flour type and the plant used. The addition of wild thyme and rosemary resulted in a significant increase in the phenolic content of wheat tortillas, while all enriched whole-grain tortillas exhibited a higher phenolic content than the control samples. The highest phenolic content in whole-grain tortillas was found in those fortified with rosemary, oregano and wild thyme. The highest antioxidant content was recorded in tortillas prepared with rosemary, irrespective of whether the flour used was refined or wholemeal. Fourteen phenolic compounds were tentatively identified in aromatic plants tested. The main phenolic compounds in Origanum vulgare were flavonoids. Rosmarinic acid was the dominant phenolic compound in rosemary and all thyme species, reaching the highest level in rosemary. Such high levels of rosmarinic acid may be responsible for the high antioxidant and total phenolic contents observed in rosemary extracts and also in tortillas when this plant is included in the recipe. The results of this study indicate that selected aromatic plants, particularly rosemary, have the potential to be utilized as functional ingredients in bakery products. By incorporating dried aromatic plants from the Lamiaceae family into wheat flour tortillas, food manufacturers can create products that not only taste better but also provide added health benefits. The use of selected herbs can improve the nutritional profile of tortillas by increasing antioxidant properties and, due to the properties of herbs, extend the shelf life of the product. Full article

Background: Palliative care focuses on the prevention of worsening health, improving the quality of the patient’s life, and the relief of suffering, and therefore has a considerable impact on both the patient suffering from a life-threatening or potentially life-threatening illness and on their family. Spirituality, as the dimension of human life involving the search for meaning, purpose, and transcendence, and connection with oneself, others, and the sacred, could be essential in supporting these patients. The aim of this study was to synthesise the scientific evidence describing the interventions and/or activities undertaken to meet the spiritual needs of the palliative patient. Methods: A literature search was carried out across the following databases: PubMed, LILACS, Scopus, and Web of Science. The PRISMA statement was used to guide this review. Results: Twenty-four articles were included. The thematic categories included spiritual needs at the end of life, the influence of music and dance as palliative care, care for family caregivers, and the comparison between counselling and dignity therapy. Conclusions: Interventions in the biopsychosocial–spiritual spheres impact on the patient’s peace of mind and promote the acceptance of a “good death”. Healthcare personnel play an essential role in the way their patients prepare for the moment of death, and the meaning and values they convey help them to accompany and welcome patients. Last but not least, universities can play a crucial role by training nurses to integrate spiritual interventions such as music and dance, or by considering the family as a unit of care. The systematic review protocol was registered in the Prospective International Register of Systematic Reviews (PROSPERO) under protocol number CRD42023490852. Full article

Elderly people make up an increasingly large part of society and the Church. The theme of old age is also increasingly present in papal teaching. This is evidenced, for example, by the series of Wednesday Catecheses on old age delivered by Pope Francis in 2022, or by the establishment of the World Day for Grandparents and the Elderly. Given the importance of the presence of the elderly, this article aims to present old age in the perspective of faith, and the importance of the presence of the elderly in the life of the Church. The author will therefore focus, first and foremost, on the view of old age as a time of thanksgiving and gratitude to God for the gift of life, for the goods received, the experiences lived, and the people encountered. Viewed from the perspective of faith, old age is also a time of preparation for death and for meeting the Risen Christ. It is therefore a time to adopt a new outlook on faith and the call to holiness. Old age is, at the same time, a period of life in which individuals can still contribute a lot to the life of the family, society, and the Church through their commitment, service, bearing witness to the faith, bearing witness to the Gospel and the values that flow from living the Gospel, through works of charity and, above all, through sharing the awareness that life is a beautiful gift from God that is worth using well and wisely. And, through the wisdom gained over the many years of their lives, elderly people become authentic witnesses of God’s love. The experience of long life and gratitude for this gift is not only relevant to Catholics and Christians, but has a universal appeal, since in any society, regardless of faith, human life should also be valued in old age. Full article