Search Results (2)

The design of a novel electrothermal microgripper device is shown, which is based on an improved chevron type actuator developed considering their elements parameterization, whose resistive model is also provided. The performance of the microgripper’s parameters, such as displacement, force, and temperature distribution, with convection for the voltage range from 0 up to 5 V, is evaluated through numerical and analytical simulation. Microgripper design was also improved with aid of parameterization. The effect on the microgripper performance due to its thickness is also analyzed, finding a considerable increment in force, when thickness increases. Its main advantage is given by the simplicity of the compliance arrangement of the microgrippers jaws. Considering convection, when 5 V are applied, 37.72 °C was generated at the jaw’s tips of the Improved Microgripper 2 (IMG2), implemented with silicon, this relatively low temperature increases its capabilities of application. When the IMG2 is implemented with polysilicon, its response is competitive comparing with a more complex microgripper, increase of displacement (50%) is shown, but a decrement of force (30%). The diameters allowed for the subjection objects are found between 84.64 µm and 108 µm, with weights lower than 612.2 µg. Some tests of subjection were performed using microcylinders of Au, glass ceramic, polycarbonate and carbon fiber, showing a permissible stress on them, considering its Young’s modulus, as well as the total reaction force induced. All simulations were done on Ansys software. The results demonstrate the feasibility of the future microgripper fabrication. Full article

Bipyridinium salts, commonly known as viologens, are π-acceptor molecules that strongly interact with π-donor compounds, such as porphyrins or amino acids, leading their self-assembling. These properties have promoted us to functionalize polysilicon microparticles with bipyridinium salts for the encapsulation and release of π-donor compounds such as catecholamines and indolamines. In this work, the synthesis and characterization of four gemini-type amphiphilic bipyridinium salts (1·4PF₆–4·4PF₆), and their immobilization either non-covalently or covalently on polysilicon surfaces and microparticles have been achieved. More importantly, they act as hosts for the subsequent incorporation of π-donor neurotransmitters such as dopamine, serotonin, adrenaline or noradrenaline. Ultraviolet-visible absorption and fluorescence spectroscopies and high-performance liquid chromatography were used to detect the formation of the complex in solution. The immobilization of bipyridinium salts and neurotransmitter incorporation on polysilicon surfaces was corroborated by contact angle measurements. The reduction in the bipyridinium moiety and the subsequent release of the neurotransmitter was achieved using ascorbic acid, or Vitamin C, as a triggering agent. Quantification of neurotransmitter encapsulated and released from the microparticles was performed using high-performance liquid chromatography. The cytotoxicity and genotoxicity studies of the bipyridinium salt 1·4PF₆, which was selected for the non-covalent functionalization of the microparticles, demonstrated its low toxicity in the mouse fibroblast cell line (3T3/NIH), the human liver carcinoma cell line (HepG2) and the human epithelial colorectal adenocarcinoma cell line (Caco-2). Full article