Search Results (789)

Background: As Information and Communication Technology (ICT) advances, the healthcare market is shifting toward a consumer-centered paradigm. This study analyzes the structural relationships between medical information quality, medical service quality, and Technology Acceptance Model (TAM) variables to determine their impact on patient satisfaction and revisit intentions in a general hospital context. Methods: An online survey was conducted with 376 consumers who had experience using general hospitals in South Korea between June and December 2024. Data were analyzed using structural equation modeling (SEM) with SPSS 29.0 and AMOS 29.0. Ethical measures, including informed consent and anonymity, were strictly followed. Results: Findings indicate that among medical information quality factors, accuracy significantly enhanced perceived usefulness, while timeliness positively influenced perceived ease of use. Regarding medical service quality, both accessibility and responsiveness significantly improved both usefulness and ease of use, with responsiveness being the most powerful predictor of ease of use (β = 0.655). While both TAM variables significantly increased patient satisfaction, only perceived ease of use and satisfaction directly drove revisit intentions; perceived usefulness influenced revisit intention only through the mediation of satisfaction. Conclusions: Patient satisfaction is a paramount factor directly influencing loyalty. Healthcare administrators should prioritize the accuracy and timeliness of digital health information while improving service responsiveness to enhance long-term hospital competitiveness in the proactive consumer era. Full article

Background and Objectives: Diabetic kidney disease (DKD) is one of the leading causes of chronic kidney disease (CKD) worldwide. Individuals over 65 years of age with type 2 diabetes mellitus (T2DM) constitute a growing age group that is frequently underrepresented in randomized clinical trials. Finerenone has been shown to reduce renal progression and cardiovascular events in patients with albuminuric DKD. To evaluate the clinical and laboratory characteristics as well as the therapeutic response and safety profile of finerenone in patients over 65 years of age with DKD, based on data from the FINDKDLATAM observational study cohort. Materials and Methods: Subgroup analysis of a real-life, retrospective, multicenter observational study—the FINDKDLATAM cohort. For the present analysis, patients aged ≥ 65 years were stratified. Sociodemographic, clinical, paraclinical, and treatment variables and adverse events were evaluated. The descriptive analysis used medians with interquartile ranges (IQRs) for continuous variables of non-parametric distribution and absolute and relative frequencies for categorical variables. The comparison of baseline parameters and those at six months of follow-up was performed using non-parametric tests, with statistics. Results: Of the total of 347 patients included in the original study, 157 (45.2%) were ≥65 years of age. The median age was 72 years. The baseline profile showed a median glomerular filtration rate (eGFR) of 38.0 mL/min/1.73 m² (IQR: 30.0–50.75), as well as elevated albuminuria (ACR 327.0 mg/g; IQR: 186.5–805.5). In addition, the patients had a high burden of comorbidities. 58.0% of patients received finerenone at a dose of 10 mg and 42.0% at a dose of 20 mg. After six months of follow-up, a significant reduction in the median ACR was observed, decreasing from 327.0 mg/g (IQR: 186.5–805.5) to 78.0 mg/g (IQR: 27.5–143.0), corresponding to a decrease of 76% (p < 0.0001). Regarding safety, hyperkalemia occurred in 20.3% of patients, although, in all cases, it was mild hyperkalemia (potassium between 5.1 and 5.5 mEq/L), with no serious episodes or treatment suspensions attributable to this event. Conclusions: In this cohort of Latin American adults over 65 years of age with albuminuric DKD, finerenone demonstrated good efficiency given the clinically significant reduction of albuminuria with stable renal function at six months of treatment, also demonstrating a safety profile, with a low risk of hyperkalemia. Full article

Hybrid healthcare integrates digital and in-person services across care delivery and governance, becoming central to modern health systems. Driven by technological advances and the COVID-19 pandemic, it reshapes care pathways, workforce organisation, and system management. Hybrid models can improve outcomes while reducing staff and administrative burdens. This paper presents a consortium-based exploratory review to conceptualise hybrid healthcare and define its core domains. Using qualitative analysis and two AI-focused case studies, it identifies five interrelated domains: operations, care pathways, education, governance, and data-driven personalised care. Findings, including evidence from Czechia, offer a practical framework for analysing hybrid healthcare transformation. Full article

Background: Breast cancer comprises 31.4% of all female cancers in Saudi Arabia (2020 Cancer Registry). Despite free national screening services existing since 2005, mammography utilization remains critically low. This study assessed breast cancer knowledge, attitudes, and practices (KAP) among females in Saudi Arabia and identified independent predictors of screening behavior. Methods: A cross-sectional study (December 2024–February 2025) enrolled 426 females aged ≥20 years from all 13 Saudi administrative regions using a quota-based design combining facility-based and online recruitment. Attitude and barrier domains were adapted from Champion’s Health Belief Model Scale (CHBMS), validated in Arabic; knowledge items used validated regional instruments. Knowledge-score reliability: KR-20 = 0.45; attitude subscale: α = 0.74. Binary logistic regression identified independent predictors of screening uptake (outcome: any screening in the preceding five years, coded as screened = 1; not screened = 0). Results: Mean composite knowledge score: 4.51 ± 1.52/7 (KR-20 = 0.45); 54.0% achieved high knowledge (≥5). Mammography uptake was 30.5% overall and 52.2% among women aged ≥40 (n = 136; the recommended target group). Predominant barriers: Fear of diagnosis (83.6%), belief in incurability (76.3%), radiation concern (73.2%), and pain anxiety (72.3%). Logistic regression (χ²(8) = 188.96, p < 0.001; McFadden’s pseudo R² = 0.323) identified older age (OR = 1.52; 95% CI: 1.21–1.92), higher income (OR = 1.57; 95% CI: 1.25–1.99), transportation barriers (OR = 3.39; 95% CI: 1.95–5.89), and family discouragement (OR = 3.03; 95% CI: 1.72–5.34) as significant predictors (all p < 0.001). Conclusions: A significant knowledge–practice gap persists across all 13 Saudi regions. These findings suggest several implications for a multi-level public health response to be evaluated through future intervention research; multi-level strategies targeting CHBMS Barriers are needed. Full article

Background: Post-stroke spasticity is a frequent and disabling consequence of stroke, including when affecting the lower limbs, where it may impair stance, gait, balance, postural control, functional independence and quality of life. Botulinum toxin type A (BoNT-A) is widely used as a focal neuromodulatory treatment for post-stroke spasticity. However, the relationship between BoNT-A-induced reduction in muscle hypertonia, objective changes in spastic muscle’s biomechanical properties, and functional outcomes such as mobility and balance remains insufficiently clarified. This systematic review aimed to synthesize recent evidence regarding the non-invasive assessment of spastic muscle properties following BoNT-A administration in post-stroke patients, with emphasis on mobility and balance outcomes. Methods: A systematic literature review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The search was performed in international electronic databases and included studies published between 1 January 2023 and 31 December 2025. The search strategy used specific keywords and keyword combinations/syntaxes, contextually, related to the topic of interest. Results: A total of 32 studies met the eligibility criteria and were included in the final data analysis and synthesis, comprising 13 primary clinical studies—6 randomized or controlled interventional studies and 7 observational studies—together with 12 reviews or evidence syntheses, 3 technical or clinical framework papers, and 4 survey, epidemiological, health-services or health-economic studies. Overall, the included articles addressed BoNT-A treatment in post-stroke spasticity, with partial focus on muscle properties, gait, mobility, and functional outcomes. However, only a limited number of studies investigated objective non-invasive assessment methods, and few directly related muscle-property changes in balance and mobility outcomes. Formal risk-of-bias assessment and quantitative synthesis were not performed because of the substantial heterogeneity of the included evidence, with only two studies being potentially suitable for pooling and these addressing different muscle groups, interventions, and outcome domains. Discussion and Conclusions: The reviewed literature confirms the clinical relevance of BoNT-A in the management of post-stroke spasticity. However, most studies assess treatment effects mainly through clinical scales, while objective evaluation of muscle stiffness, elasticity, viscoelastic properties, and their relationship with mobility and balance remains limited. Although some studies address gait, functional recovery, or muscle-related changes, the combined use of BoNT-A treatment, myotonometric assessment, and proprioceptive–stabilometric evaluation is largely absent. Therefore, current evidence highlights an important research gap and supports the need for future longitudinal studies integrating non-invasive biomechanical and balance assessment tools to better monitor treatment response and guide individualized neurorehabilitation in post-stroke patients. Full article

Youth substance abuse represents a complex social and security problem which cannot be adequately captured solely through crime statistics. In the context of the Slovak Republic, there is a lack of systematic research linking healthcare data on intoxications with criminological indicators, which limits the effective design of preventive measures. The research analyses substance abuse (according to ICD 10 F10–F19) among youth in the NUTS 3 regions of the Slovak Republic during 2019–2024 and their descriptive association with drug-related crime. Analysis is based on data provided by public administration entities—the National Health Information Centre of the Slovak Republic (data on youth hospitalisation), the Operational Centre of the Emergency Medical Service of the Slovak Republic (data on EMS call-outs) and the Ministry of Interior of the Slovak Republic (data on crime). The provided data represent the whole population of the Slovak Republic. To enable comparison between datasets, two standardised indices are constructed: an EMS index representing a number of EMS call-outs and urgent hospitalisations per 100,000 inhabitants of the respective youth age group and a crime index representing a number of drug-related criminal offences per 100,000 total regional inhabitants. A total of 4486 emergency interventions with F10–F19 diagnoses were identified, with the highest proportion being disorders caused by alcohol (F10), more common among juveniles (14–17) than in minors (6–13). The analysis identifies a moderate positive association between the regional EMS index for F10 and F11–F19 diagnoses (correl youth = 0.66; correl juveniles = 0.55) and a weak negative association between the F11–F19 EMS index and the drug-related crime index (correl youth = −0.28; correl minors = −0.52). The Pearson correlation coefficients are reported as descriptive indicators. Formal statistical inference was not the aim of this study. The findings suggest that crime statistics alone inadequately reflect the health risks of youth substance abuse, underscoring the need to link healthcare, criminological, and demographic data and to develop regionally targeted prevention. Full article

Background/Objectives: Dementia poses a major public health challenge in South Korea, where population ageing has accelerated rapidly. We aimed to describe national 2016–2025 dementia prevalence trends and to generate a one-year 2026 forecast using NHIS-linked administrative data. Methods: We performed a retrospective longitudinal analysis of de-identified aggregate administrative data from the Ministry of Health and Welfare Municipal and District Dementia Status Report (2016–2025) and NHIS age–sex pivot table records. This was a purely descriptive and forecasting analysis; no inferential statistical tests were applied. Descriptive statistics were computed for national, sex-stratified, regional, and age-stratified outcomes. For the 2026 forecast, we used a prespecified demographic-offset time-series approach: the population aged 65 years or older and the estimated prevalence rate were modelled separately using damped-trend Holt exponential smoothing, then recombined to estimate patient count. Residual bootstrap resampling (20,000 iterations) was used to derive a 95% prediction interval for the patient count. A sensitivity analysis using ARIMA(1,1,0). Results: 602,633 (8.89%) in 2016 to 955,585 (9.09%) in 2025, a 58.6% increase. Females consistently showed higher prevalence than males (2025: 9.55% vs. 8.52%), and regional analysis identified South Jeolla Province (10.17%) as the highest-prevalence region and Ulsan Metropolitan City (8.10%) as the lowest. The female-to-male cumulative rate ratio reached 2.49 in the ≥85-year group. The primary 2026 forecast estimated 1,003,407 dementia patients among adults aged 65 years or older, with an estimated prevalence of 9.19% and a 95% prediction interval of 983,838–1,022,158. Conclusions: South Korea’s rising dementia burden is primarily driven by population ageing rather than a sharp increase in age-specific prevalence. The 2026 forecast supports urgent planning for a national dementia care population of approximately one million people. Full article

Background/Objectives: Health systems across Europe are increasingly challenged by population ageing, multimorbidity, and persistent inequities in access to care. Community Nursing has emerged as a promising approach to strengthening preventive, community-based services, yet evidence on stakeholder-perceived needs during early implementation remains limited. This study aimed to explore how different types of needs are perceived and articulated during the early implementation of Community Nursing in Austria. Methods: An interpretive descriptive qualitative study was conducted as part of an Austrian Community Nursing pilot project. Semi-structured interviews were carried out with eleven stakeholders, including informal caregivers, network partners (e.g., local healthcare providers), and local political decision-makers. Data were analyzed using qualitative content analysis, guided deductively by Bradshaw’s Taxonomy of Needs and complemented by inductive sub-category development. Interviews were conducted via telephone or video call (Zoom) and ranged from approximately 30 min to an hour. Results: Normative needs reflected expectations for preventive services, continuity of care, advocacy, and sustainable organizational structures. Felt needs centered on trust, emotional security, and relational continuity. Expressed needs became visible through active use of Community Nursing services, including preventive programs, transitional care support, and administrative navigation. Comparative needs highlighted geographic inequities and differences between municipalities with and without access to Community Nursing. Across stakeholder groups, concerns regarding long-term financing and sustainability were prominent. Conclusions: The findings suggest that Community Nursing addresses multiple stakeholder-perceived needs simultaneously, particularly by providing relational, accessible, and preventive support. However, sustained impact depends on stable funding and systemic integration beyond pilot phases. These results offer transferable insights for the development and scaling of community-based nursing models in ageing societies. Full article

In recent years, numerous countries have recorded a steady increase in opioid use. Although prescribing practices vary considerably among them, fentanyl is among the most frequently prescribed strong opioids in several European countries and in Spain. In this study, we analyzed the evolution of outpatient fentanyl dispensing in Galicia, Spain, between January 2019 and December 2025, using the Anatomical Therapeutic Chemical Classification/Defined Daily Dose (ATC/DDD) system. We paid particular attention to differences between provinces and explored temporal trends broken down by route of administration (buccal, nasal, sublingual and transdermal). Dispensing data were obtained from the General Sub-directorate of Pharmacy of the Galician Health Service (SERGAS) from the monthly billing database of official prescriptions dispensed in Galician pharmacies and were expressed as defined daily dose per 1000 inhabitants per day (DID). Dispensing rates between provinces were compared using the non-parametric Kruskal–Wallis test, considering a p-value less than 0.05 as statistically significant. We observed an increase in fentanyl use between 2019 and 2021, followed by a systematic decrease during the 2022–2025 period. Significant differences (p < 0.001) were found in the defined daily dose per 1000 inhabitants per day (DID) among the four Galician provinces, and demographic and socioeconomic factors partially explain the observed disparities. Regarding pharmaceutical presentations, transdermal patches were the most frequently used form during the study period. While some limitations should be noted, the results suggest that the observed decrease in fentanyl dispensing in Galicia could be associated with the implementation of the Ministry of Health’s 2021 optimization plan, with a sustained reduction in its dispensing from 2022 onwards. However, it is necessary to maintain pharmacovigilance at the provincial level. Full article

Background/Objectives: Community-based drug rehabilitation is a key component of public health strategies in China, with anti-drug social workers playing a frontline role in relapse prevention, social reintegration, and long-term recovery. However, the sustainability and effectiveness of this workforce remain uncertain due to complex organisational and structural conditions. This study aims to examine the professional roles, work-related challenges, and coping strategies of anti-drug social workers within community-based rehabilitation systems. Methods: A systematic review was conducted in accordance with PRISMA 2020 guidelines and was registered in PROSPERO (Registration ID: 1381833). The literature published between 2009 and 2025 was identified through Google Scholar, PubMed, Web of Science, and the Electronic Library. A total of 35 Chinese and English-language studies met the inclusion criteria and were analysed to synthesise evidence on social work practice in drug rehabilitation contexts. Results: The findings identify three core professional roles: information provider, resource linker, and relationship repairer. These roles highlight the multifaceted contribution of social workers in bridging institutional systems and client needs. However, their effectiveness is constrained by fragmented governance structures, role conflict, professional identity ambiguity, administrative burden, limited training, and sustained emotional labour. These conditions contribute to occupational stress, burnout risk, and workforce instability, which weaken service continuity and client-centred care. Conclusions: Strengthening community-based drug rehabilitation requires addressing workforce and system-level constraints. Clearer role definition, targeted interdisciplinary training, reduced administrative demands, and structured organisational support are essential to enhance professional capacity, improve service delivery, and support long-term recovery outcomes. Full article

Background/Objectives: Standardised institutional patient satisfaction surveys are the primary quality-monitoring tool in Romanian public hospitals, but their ability to capture the full range of patient experiences remains uncertain. This study quantifies the discrepancy between institutional patient satisfaction scores and an independent, unmediated national feedback instrument, the Patient Feedback Mechanism (MFP), at Targoviste County Emergency Hospital (SJUT) over a six-year period (2019–2024), and examines item-level MFP results across eight dimensions of the patient experience, including dimensions not captured by the institutional indicators routinely reported by SMCSP. Methods: A sequential design combined six years of institutional satisfaction data (2019–2024) from SJUT (N = 32,176 questionnaires) with item-level MFP results for the same period, covering eight questions on medical services, cleanliness, out-of-pocket medication costs, staff involvement, communication, recommendation intent, self-reported health outcome, and willingness to report requests for money from staff. Hypotheses were tested using two-proportion z-tests with Wilson confidence intervals, Mann–Kendall trend analysis, and Cohen’s h for effect sizes. Results: Institutional satisfaction remained consistently high (96.88–97.45%), while MFP satisfaction with medical services ranged from 70.7% to 88.9% across the same years, yielding gaps of 7.9 to 26.7 percentage points, significant in every year (p < 0.001; Cohen’s h ranging from 0.32 to 0.82). The gap did not follow a monotonic trend (Mann–Kendall p = 0.469); instead, it widened to a peak in 2021 and narrowed progressively through 2024. A parallel comparison between the Quality and Patient Safety Management Service (SMCSP) overall impression item (exceeding 99%) and the MFP recommendation item (69.9–76.3%) showed even larger gaps, of 23.3 to 29.6 percentage points. The MFP item on willingness to report requests for money from staff, which is not part of SMCSP’s reported institutional indicators, remained in a narrow 4.0–5.5% range between 2019 and 2023 with no significant trend (Mann–Kendall p = 0.82); a higher 2024 value (6.9%) coincides with a national redesign of this item and is not directly comparable to earlier years. Conclusions: Institutional surveys and an independent national feedback instrument offer structurally distinct perspectives on hospital performance, reflecting differences in administration rather than equivalent estimates of patient satisfaction. The discrepancy between sources is significant and persistent, though not monotonic, widening sharply during 2021 before narrowing. One item with no institutional equivalent documents a measurable, non-trivial proportion of patients willing to report informal payment requests every year, although the available data do not establish whether this proportion is rising over time. Systematic use of existing MFP data, already collected nationally, can complement institutional surveys at minimal additional cost, provided the two instruments are interpreted as structurally different rather than as alternative estimates of the same quantity. Full article

Background: Measles remains a significant public health challenge in Ethiopia, and the country has not achieved measles elimination despite the commitments outlined in the Immunization Agenda 2030. This study assessed inequalities in MCV2 vaccination among children aged 24–35 months in Ethiopia. Methods: This study used nationally representative data from the 2022/23 National Health Equity Survey, which employed a two-stage stratified cluster sampling design across all regions and city administrations. A total of 1987 mothers/caregivers of eligible children were interviewed. Descriptive statistics, bivariable analyses, and multivariable logistic regression were conducted using Stata 17 software, and determinants of MCV2 uptake were identified. Wealth-related inequality was assessed using concentration index analysis. Statistical significance was set at p < 0.05. Results: Overall MCV2 coverage was 60.4%. The multivariable analysis identified a significant inequality in second-dose measles vaccination (MCV2) in Ethiopia. Children born in health facilities had higher odds of vaccination (AOR = 1.88; 95% CI: 1.49–2.38), and maternal age of 25–34 years was associated with increased uptake compared to younger mothers (AOR = 2.03; 95% CI: 1.18–3.48). Postnatal care utilization and vitamin A supplementation strongly improved vaccination coverage, with children receiving vitamin A showing markedly higher odds of MCV2 uptake (AOR = 16.74; 95% CI: 9.61–29.14). Female children were more likely to be vaccinated than males (AOR = 1.50; 95% CI: 1.01–2.24), and higher maternal education (college or above) significantly increased uptake (AOR = 2.78; 95% CI: 1.02–7.73). Wealth status also influenced coverage. Conclusions: Improving MCV2 coverage in Ethiopia requires strengthening of maternal and child health services and promotion of integrated care, including PNC, vitamin A supplementation, and routine immunization. Early and consistent contact with the health system, along with addressing gaps in health education and supporting younger mothers, is essential. Persistent inequalities by place of birth, household wealth, and region highlight the need for targeted interventions. Strengthening equitable immunization services remains critical to achieving national and global measles elimination goals. Full article

Background: Despite being considered a country with a larger health workforce in Africa, the South African health workforce continues to experience shortages and a maldistribution of health workers across regions and sectors. Current projections suggest that the workforce is expected to decline further, especially among doctors, nurses and midwives, in large part, due to attrition—which could compromise the delivery of primary health and maternity services. These health workforce shortages and uneven distribution threaten the sustainability and effectiveness of health services in South Africa and drives the need to investigate the factors that may be influencing career choice and change decisions among health professionals in South Africa. Methods: A qualitative exploratory study, making use of purposive sampling and semi-structured interviews, was conducted to investigate the factors influencing career choice and change decisions among health professionals in South Africa. The participants were qualified health professionals in the fields of medicine, nutrition, pharmacy, nursing, and psychology working in the private, public, and academic sectors. Data was collected until saturation was achieved and then thematically analyzed using MAXQDA 24. Results: A total of 10 participants made up of three males and seven females were interviewed. These participants worked in different employment sectors with some having dual roles in private practice, public sector, and academia. The analysis revealed three major themes that capture the nature of and factors influencing career choice and career changes occurring in South Africa. The first theme related to factors influencing career choice (including altruism, family influence, personal experiences, financial/job security, academic achievement, career guidance, and opportunity for change). The second theme focused on career change dynamics (nature of career changes and career transitions occurring in the form of specialization, switching health professions, exiting health professions, adding non-health interests, and shifting focus areas). The third theme revealed factors influencing career change. These were categorized into personal and individual factors, workplace or job-specific factors, and administrative factors. This study has contributed to understanding the career choices and career changes taking place within the health professions in South Africa. It has also revealed a need for reforms in policy and practice for the current health professionals who have no intention of changing their careers while highlighting implications for future training of health professionals. Also, addressing the challenges of poor working conditions, lack of support, unemployment and placement delays, and other administrative barriers will help mitigate some of the issues leading to health workforce shortages and inequities in the South African context. Conclusions: The strongest motivator for choosing a career in health professions is the desire to care for others, while retention of the health workforce is challenged by personal, workplace, and administrative factors. Enhancing workplace conditions and support systems, implementing policy reforms, and minimizing administrative barriers is essential for achieving universal health coverage and sustaining a resilient health workforce in South Africa. Full article

Background/Objectives: People with disabilities face a disproportionately higher disease burden alongside reduced healthcare accessibility, resulting in elevated unmet healthcare needs (UHN). Understanding the factors that drive UHN—and whether these factors differ by disability status—is critical for developing targeted public health interventions. Methods: A secondary cross-sectional analysis was conducted using linked national survey and administrative data—specifically the Korea National Health and Nutrition Examination Survey (KNHANES) cycles VI to VIII (2013–2021) linked with National Health Insurance Service (NHIS) administrative records—to examine determinants of healthcare access and utilization barriers by disability status. Independent variables were selected based on Andersen’s Behavioral Model of Health Services Use for vulnerable populations, encompassing predisposing factors, enabling factors, and need factors (including functional status indicators). Interaction terms between disability status and sex, and between disability status and household income level, were introduced to identify effect modification by disability status. Results: People with registered disabilities had significantly higher UHN compared to those without disabilities. The contributing factors to UHN differed between the two groups, with sex and household income showing statistically significant interaction effects with disability status, indicating that their associations with UHN vary depending on whether an individual has a registered disability. Conclusions: UHN in people with disabilities is shaped by a distinct set of determinants compared to the general population. The overall pattern of contributing factors differed between people with and without disabilities across multiple dimensions. These findings highlight the need for tailored healthcare policies that account for the unique vulnerabilities of people with disabilities, rather than applying uniform strategies across all population groups. Full article

Background and Objectives: Artificial intelligence (AI) is increasingly integrated into healthcare management and pharmaceutical marketing workflows, yet determinants of AI adoption intention among non-clinical professionals remain under-studied in Central and Eastern Europe. This cross-sectional study quantified AI adoption intention (AAI) across three professional groups and examined its organizational, cognitive, attitudinal, and regulatory correlates. Methods: We surveyed 127 Romanian professionals (43 hospital administrators, 42 pharmaceutical marketing professionals, 42 community pharmacy managers) using a 46-item structured instrument. The instrument combined items adapted from UTAUT/TAM and organizational-readiness measures with study-specific AI-marketing, AI-literacy, and regulatory-literacy items; Analyses included ANOVA with Tukey HSD, Spearman correlations, age-adjusted OLS regression with HC3 robust standard errors, bootstrap indirect-effect analysis, moderation, exploratory k-means clustering, and exploratory logistic/ROC analysis. Results: AAI differed across groups: pharmaceutical marketing 4.33 ± 0.50, hospital administrators 3.39 ± 0.47, and pharmacy managers 2.88 ± 0.54; all pairwise Tukey contrasts p < 0.001. In the multivariable model (R² = 0.833)—interpreted cautiously because conceptually related adoption constructs may overlap despite acceptable collinearity diagnostics—perceived usefulness, organizational readiness, and perceived ease of use were the strongest associated factors, while data governance concern was the main negative correlate. Perceived usefulness statistically accounted for 61.7% of the AI literacy–AAI indirect association, and regulatory literacy moderated the AI literacy–AAI association. An exploratory age-adjusted logistic model showed high within-sample discrimination for top-tertile AAI but should be interpreted as convergent validity among survey constructs rather than as a validated screening tool. Conclusions: AI adoption intention in Romanian medical management and pharmaceutical marketing is associated mainly with perceived usefulness and organizational readiness, tempered by data governance concern and regulatory knowledge. Longitudinal, multi-site, real-world implementation studies with external validation are needed. Full article